Chemical Approach to Positional Isomers of Glucose-Platinum Conjugates Reveals Specific Cancer Targeting through Glucose-Transporter-Mediated Uptake in Vitro and in Vivo

Chemistry

• Antitumor 9%
• Bioactivity 18%
• Compound Isomer 27%
• Conjugate 36%
• Cytochalasin B 9%
• Cytotoxicity 9%
• Diatomic Carbon 27%
• Glucose 100%
• Glycoconjugates 9%
• Inhibitor 9%
• Platinum 63%
• Point Group C1 36%
• Point Group C3 18%
• Point Group C4 9%
• Point Group C6 9%
• Synthesis (Chemical) 9%
• Toxicity 9%

Pharmacology, Toxicology and Pharmaceutical Science

• Absence 9%
• Biological Activity 18%
• Breast Cancer 9%
• Cytochalasin B 9%
• Cytotoxicity 9%
• Glucose 81%
• Glucose Transporter 9%
• Glucose Transporter 1 72%
• Glycoconjugate 9%
• Malignant Neoplasm 45%
• Mouse Model 9%
• Neoplasm 9%
• Platinum 63%
• Toxicity 9%

Biochemistry, Genetics and Molecular Biology

• Antineoplastic Activity 9%
• Aptitude 9%
• Biological Activity 18%
• Cancer Cell 9%
• Conjugate 36%
• Cytotoxicity 9%
• Glucose 81%
• Glucose Transporter 18%
• GLUT1 63%
• Glycoconjugate 9%
• Internalization 9%
• Isomer 27%
• Mouse Model 9%
• Position 18%
• Syngenic 9%
• Synthesis 9%