Chemistry of insect antifeedants from Azadirachta indica (Part 20): Synthesis of biologically active, simple analogues of azadirachtin, containing the hydroxytetrahydrofurancarboxylate hemiketal moiety

  • María L. De La Puente
  • , Robert B. Grossman
  • , Steven V. Ley
  • , Monique S.J. Simmonds
  • , Wally M. Blaney

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

A synthetic route to mimics of the insect antifeedant azadirachtin 1 containing the hydroxytetrahydrofurancarboxylate hemiketal functional moiety has been developed. Two of these compounds, 2 and 11, show significant antifeedant activity against Spodoptera littoralis, although they are not as active as azadirachtin.

Original languageEnglish
Pages (from-to)1517-1521
Number of pages5
JournalJournal of the Chemical Society - Perkin Transactions 1
Issue number13
DOIs
StatePublished - Jul 7 1996

ASJC Scopus subject areas

  • General Chemistry

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