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Chemo Brain (Chemo Fog) as a potential side effect of doxorubicin administration: Role of cytokine-induced, oxidative/nitrosative stress in cognitive dysfunction

  • Christopher D. Aluise
  • , Rukhsana Sultana
  • , Jitbangjong Tangpong
  • , Mary Vore
  • , Daret St. Clair
  • , Jeffrey A. Moscow
  • , D. Allan Butterfield

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

107 Scopus citations

Abstract

Doxorubicin (ADRIAMYCIN, RUBEX) is a chemotherapeutic agent that is commonly administered to breast cancer patients in standard chemotherapy regimens. As true of all such therapeutic cytotoxic agents, it can damage normal, noncancerous cells and might affect biochemical processes in a manner that might lead to, or contribute to, chemotherapy-induced cognitive deficits when administered either alone or in combination with other agents.

Original languageEnglish
Title of host publicationChemo Fog
Subtitle of host publicationCancer Chemotherapy-Related Cognitive Impairment
EditorsRobert Raffa, Ronald Tallarida
Pages147-156
Number of pages10
DOIs
StatePublished - 2010

Publication series

NameAdvances in Experimental Medicine and Biology
Volume678
ISSN (Print)0065-2598

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology

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