Abstract
Emerging synthetic development of chiral gold(iii) complexes has prompted new opportunities in catalysis and material science with limited utility in biomedicine. Here, we demonstrate potential chemotherapeutic capability of [C^N]Au(iii)Cl(R-DuPhos) (1-7) complexes, containing 1,2-bis[(2R,5R)-2,5-dialkylphospholano]benzene, which shows good stabilty, potent anticancer activity, and tolerability in mice.
Original language | English |
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Pages (from-to) | 10237-10240 |
Number of pages | 4 |
Journal | Chemical Communications |
Volume | 58 |
Issue number | 73 |
DOIs | |
State | Published - Aug 16 2022 |
Bibliographical note
Publisher Copyright:© 2022 The Royal Society of Chemistry.
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- General Chemistry
- Ceramics and Composites
- Metals and Alloys
- Materials Chemistry
- Surfaces, Coatings and Films
- Catalysis