Emerging synthetic development of chiral gold(iii) complexes has prompted new opportunities in catalysis and material science with limited utility in biomedicine. Here, we demonstrate potential chemotherapeutic capability of [C^N]Au(iii)Cl(R-DuPhos) (1-7) complexes, containing 1,2-bis[(2R,5R)-2,5-dialkylphospholano]benzene, which shows good stabilty, potent anticancer activity, and tolerability in mice.
|Number of pages||4|
|State||Published - Aug 16 2022|
Bibliographical notePublisher Copyright:
© 2022 The Royal Society of Chemistry.
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Ceramics and Composites
- Chemistry (all)
- Surfaces, Coatings and Films
- Metals and Alloys
- Materials Chemistry