Cigarette Mentholation Increases Smokers' Exhaled Carbon Monoxide Levels

Gregory E. Miller, Murray E. Jarvik, Nicholas H. Caskey, Suzanne C. Segerstrom, Martin R. Rosenblatt, William J. McCarthy

Research output: Contribution to journalArticlepeer-review

32 Scopus citations


Male smokers (N = 12) participated in 3 controlled-dose smoking sessions spaced 1 week apart. In each session, Ss inhaled 1, 200 cc of cigarette smoke. Menthol dosage varied across sessions, such that Ss smoked experimental cigarettes that had been injected with 0 mg, 4 mg, or 8 mg of menthol. Exhaled carbon monoxide levels increased concomitantly with menthol dosage. There were no differences in smoking topography across the 3 conditions. The ability of menthol to increase the toxicity of cigarette smoke by raising carbon monoxide levels is discussed. Results suggest that menthol cigarette preference may account for some of the racial differences in smoking behavior and smoking-related outcomes found in past literature.

Original languageEnglish
Pages (from-to)154-160
Number of pages7
JournalExperimental and Clinical Psychopharmacology
Issue number2
StatePublished - May 1994

Bibliographical note

Copyright 2018 Elsevier B.V., All rights reserved.

ASJC Scopus subject areas

  • Pharmacology
  • Psychiatry and Mental health
  • Pharmacology (medical)


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