Abstract
This study examined the effects of 6 weeks of conjugated linoleic acid (CLA) supplementation and moderate aerobic exercise on peak oxygen uptake (V̇O2 peak), the gas exchange threshold (GET), the respiratory compensation point (RCP), and serum concentrations of cholesterol, triacylglycerol, and glucose in humans. Thirty-four untrained to moderately trained men (mean ± SD; age = 21.5 ± 2.8 years; mass = 77.2 ± 9.5 kg) completed this double-blind, placebo controlled study and were randomly assigned to either a CLA (Clarinol A-80; n = 18) or placebo (PLA; sunflower oil; n = 16) group. Prior to and following 6 weeks of aerobic training (50 % V̇O2 peak for 30 min, twice per week) and supplementation (5.63 g of total CLA isomers [of which 2.67 g was c9, t11 and 2.67 g was t10, c12] or 7.35 g high oleic sunflower oil per day), each participant completed an incremental cycle ergometer test to exhaustion to determine their V̇O 2 peak, GET, and RCP and fasted blood draws were performed to measure serum concentrations of cholesterol, triacylglycerol, and glucose. Serum triacylglycerol concentrations were lower (p < 0.05) in the CLA than the PLA group. For V̇O2 peak and glucose, there were group × time interactions (p < 0.05), however, post hoc statistical tests did not reveal any differences (p > 0.05) between the CLA and PLA groups. GET and RCP increased (p < 0.05) from pre- to post-training for both the CLA and PLA groups. Overall, these data suggested that CLA and aerobic exercise may have synergistic, blood triacylglycerol lowering effects, although CLA may be ineffective for enhancing aerobic exercise performance in conjunction with a 6-week aerobic exercise training program in college-age men.
Original language | English |
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Pages (from-to) | 871-880 |
Number of pages | 10 |
Journal | Lipids |
Volume | 49 |
Issue number | 9 |
DOIs | |
State | Published - Sep 2014 |
Bibliographical note
Funding Information:Acknowledgments This study was funded by a research grant from Stepan Specialty Products, LLC and in part by the University of Nebraska Agricultural Research Division with funds provided through the Hatch Act. Neither Stepan Specialty Products, LLC nor the University of Nebraska Agricultural Research Division had any involvement in the data collection, analysis and interpretation of the data, writing of the manuscript, or in the decision to submit the manuscript for publication. The results of the present study do not constitute endorsement of the product by the authors.
Funding
Acknowledgments This study was funded by a research grant from Stepan Specialty Products, LLC and in part by the University of Nebraska Agricultural Research Division with funds provided through the Hatch Act. Neither Stepan Specialty Products, LLC nor the University of Nebraska Agricultural Research Division had any involvement in the data collection, analysis and interpretation of the data, writing of the manuscript, or in the decision to submit the manuscript for publication. The results of the present study do not constitute endorsement of the product by the authors.
Funders | Funder number |
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Stepan Specialty Products, LLC | |
University of Nebraska Agricultural Research Division |
Keywords
- Endurance
- Fatigue threshold
- Lipids
- Octadecadienoic acid
- Training
- Triglycerides
ASJC Scopus subject areas
- Biochemistry
- Organic Chemistry
- Cell Biology