Coatings on mammalian cells: Interfacing cells with their environment 06 Biological Sciences 0601 Biochemistry and Cell Biology

Kara A. Davis, Pei Jung Wu, Calvin F. Cahall, Cong Li, Anuhya Gottipati, Brad J. Berron

Research output: Contribution to journalReview articlepeer-review

25 Scopus citations

Abstract

The research community is intent on harnessing increasingly complex biological building blocks. At present, cells represent a highly functional component for integration into higher order systems. In this review, we discuss the current application space for cellular coating technologies and emphasize the relationship between the target application and coating design. We also discuss how the cell and the coating interact in common analytical techniques, and where caution must be exercised in the interpretation of results. Finally, we look ahead at emerging application areas that are ideal for innovation in cellular coatings. In all, cellular coatings leverage the machinery unique to specific cell types, and the opportunities derived from these hybrid assemblies have yet to be fully realized.

Original languageEnglish
Article number5
JournalJournal of Biological Engineering
Volume13
Issue number1
DOIs
StatePublished - Jan 17 2019

Bibliographical note

Publisher Copyright:
© 2019 The Author(s).

Keywords

  • Cell therapy
  • Cellular coatings
  • Coatings
  • Mammalian cells
  • Polymers

ASJC Scopus subject areas

  • Environmental Engineering
  • Biomedical Engineering
  • Molecular Biology
  • Cell Biology

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