Cohort studies

Deepa Valvi, Steven Browning

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

This chapter provides readers with the critical concepts to consider in designing and analyzing cohort studies. A cohort study is a powerful tool and suitable choice for conducting research for rare exposures in human populations. It can be used to assess associations between multiple exposures and multiple outcomes and identifying the risk factors and causes of diseases. The learning objectives of this chapter are as follows: (1) introduce a cohort study and its uses; (2) describe the design of a cohort study; (3) explain and differentiate the different types of cohort studies including retrospective, prospective, and ambi-directional designs; (4) discuss the selection of study populations, with sources of information on exposure, outcomes, and other key variables; (5) describe approaches to data analysis, including the calculation of person-time, with examples; (6) provide various examples of cohort studies; (7) explain advantages and disadvantages of cohort studies; and (8) discuss potential biases in cohort studies.

Original languageEnglish
Title of host publicationStatistical Approaches for Epidemiology
Subtitle of host publicationFrom Concept to Application
Pages57-75
Number of pages19
ISBN (Electronic)9783031417849
DOIs
StatePublished - Dec 12 2023

Bibliographical note

Publisher Copyright:
© The Author(s), under exclusive license to Springer Nature Switzerland AG 2024. All rights reserved.

Keywords

  • Cohort study
  • Prospective study
  • Retrospective study

ASJC Scopus subject areas

  • General Mathematics
  • General Medicine

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