Commentary on Camell et al., Aging Induces Nlrp3 Inflammasome Dependent Adipose B Cell Expansion to Impair Metabolic Homeostasis

Sara SantaCruz-Calvo; Lucia SantaCruz-Calvo; Barbara S. Nikolajczyk

doi:10.20900/immunometab20200011

Commentary on Camell et al., Aging Induces Nlrp3 Inflammasome Dependent Adipose B Cell Expansion to Impair Metabolic Homeostasis

Sara SantaCruz-Calvo, Lucia SantaCruz-Calvo, Barbara S. Nikolajczyk

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Abstract

The burden of aging and obesity is urging extended investigation into the molecular mechanisms that underlie chronic adipose tissue inflammation. B cell-targeted therapies are emerging as novel tools to modulate the immune system and thereby mitigate aging and obesity-related metabolic complications.

Original language	English
Article number	e200011
Journal	Immunometabolism (United States)
Volume	2
Issue number	2
DOIs	https://doi.org/10.20900/immunometab20200011
State	Published - Apr 20 2020

Bibliographical note

Publisher Copyright:
Copyright © 2020 by the author(s).

Keywords

adipose tissue
aging
B cells
FALC
inflammation
obesity

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Immunology and Allergy

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.20900/immunometab20200011

Cite this

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title = "Commentary on Camell et al., Aging Induces Nlrp3 Inflammasome Dependent Adipose B Cell Expansion to Impair Metabolic Homeostasis",

abstract = "The burden of aging and obesity is urging extended investigation into the molecular mechanisms that underlie chronic adipose tissue inflammation. B cell-targeted therapies are emerging as novel tools to modulate the immune system and thereby mitigate aging and obesity-related metabolic complications.",

keywords = "adipose tissue, aging, B cells, FALC, inflammation, obesity",

author = "Sara SantaCruz-Calvo and Lucia SantaCruz-Calvo and Nikolajczyk, {Barbara S.}",

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year = "2020",

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doi = "10.20900/immunometab20200011",

language = "English",

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AU - SantaCruz-Calvo, Sara

AU - SantaCruz-Calvo, Lucia

AU - Nikolajczyk, Barbara S.

PY - 2020/4/20

Y1 - 2020/4/20

N2 - The burden of aging and obesity is urging extended investigation into the molecular mechanisms that underlie chronic adipose tissue inflammation. B cell-targeted therapies are emerging as novel tools to modulate the immune system and thereby mitigate aging and obesity-related metabolic complications.

AB - The burden of aging and obesity is urging extended investigation into the molecular mechanisms that underlie chronic adipose tissue inflammation. B cell-targeted therapies are emerging as novel tools to modulate the immune system and thereby mitigate aging and obesity-related metabolic complications.

KW - adipose tissue

KW - aging

KW - B cells

KW - FALC

KW - inflammation

KW - obesity

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DO - 10.20900/immunometab20200011

M3 - Review article

AN - SCOPUS:85118180036

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Commentary on Camell et al., Aging Induces Nlrp3 Inflammasome Dependent Adipose B Cell Expansion to Impair Metabolic Homeostasis

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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Cite this