Comparative Effectiveness Research

Ashley I. Martinez, Emily S. Brouwer, Daniela C. Moga

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


As evidence-based medicine has taken a forefront in medical practice, health care providers, patients, regulatory agencies, academic researchers, and pharmaceutical industry members have desired a more complete body of data relating to real-world clinical scenarios. Comparative-effectiveness research (CER) has taken the center stage on this issue in the last two decades as it compares different clinical and public health interventions to identify the ones that work best for improving health in different populations. CER has evolved through innovative methodology and unique public–private consortiums to enhance clinical and system-wide decision-making around the world.

Original languageEnglish
Title of host publicationEncyclopedia of Pharmacy Practice and Clinical Pharmacy
Subtitle of host publicationVolumes 1-3
ISBN (Electronic)9780128127360
StatePublished - Jan 1 2019

Bibliographical note

Publisher Copyright:
© 2019 Elsevier Inc. All rights reserved.


  • Comparative effectiveness
  • Observational research
  • Patient-centered outcomes research
  • Pragmatic trials
  • Regulatory agencies

ASJC Scopus subject areas

  • General Pharmacology, Toxicology and Pharmaceutics
  • General Medicine


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