Abstract
One hundred acute leukemia cell samples (89 ALL, 11 AMML) derived from children's bone marrow at diagnosis were typed for the reaction with 15 monoclonal antibodies (mAbs). Subdivision in ALL-subgroups was performed according to conventional markers. Only some mAbs like VIL-A1 which is directed against the cALL-antigen, can substitute polyclonal rabbit antisera. Additional subclassifications became evident by the use of mAbs for T-cell differentiated ALL forms. However, unexpected negative reactions must be taken into account as observed for all T-directed mAbs with individual T-cell ALL samples.
| Original language | English |
|---|---|
| Pages (from-to) | 95-100 |
| Number of pages | 6 |
| Journal | Annals of Hematology |
| Volume | 44 |
| Issue number | 2 |
| DOIs | |
| State | Published - Feb 1982 |
Keywords
- Acute lymphatic leukemia
- Leukemia markers
- Monoclonal antibodies
ASJC Scopus subject areas
- Hematology
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