Comparison of two power densities on the healing of palatal wounds after connective tissue graft removal: randomized clinical trial

Felipe Lucas da Silva Neves, Camila Augusto Silveira, Stephanie Botti Fernandes Dias, Milton Santamaria Júnior, Andrea Carvalho de Marco, Warley David Kerbauy, Antonio Braulino de Melo Filho, Maria Aparecida Neves Jardini, Mauro Pedrine Santamaria

Research output: Contribution to journalArticlepeer-review

33 Scopus citations


Connective tissue graft (CTG), which is considered to be among the best techniques for treating gingival recession, has presented stable long-term results. However, this technique causes morbidity and discomfort in the palatine region due to graft removal at that site. A previous study reports that photobiomodulation (PBM) using a dosage of 15 J/cm2 may improve wound healing and the patient’s postoperative comfort. However, no other studies in the literature provide the best application dosage or comparisons between protocols for this purpose. The aim of this study is to compare two power densities of PBM on the wound-healing process of the donor palatine area after CTG removal. In this study, 51 patients presenting buccal gingival recession were randomized into one of the following groups: group 1: CTG procedure for root coverage and PBM application at the donor site using a 60 J/cm2 dose; group 2: CTG and PBM application using a 30 J/cm2 dose; or group 3: CTG and sham application. The evaluated parameters were the wound remaining area (WRA), scar and tissue colorimetry (TC), tissue thickness (TT), and postoperative discomfort (D), evaluated at baseline and 7, 14, 45, 60, and 90 days after surgery. Group 1 presented statistically significant smaller wounds at day 7 (p > 0.05). None of the patients presented scars at the operated area, and all of the patients reported mild discomfort, with low consumption of analgesic pills. We concluded that the protocol of 60 J/cm2 provided faster wound healing 7 days after removing the connective tissue graft for root coverage. Trial registration: (NCT02580357)

Original languageEnglish
Pages (from-to)1371-1378
Number of pages8
JournalLasers in Medical Science
Issue number7
StatePublished - Sep 1 2016

Bibliographical note

Publisher Copyright:
© 2016, Springer-Verlag London.


  • Connective tissue graft
  • Gingival recession
  • Low-level laser therapy
  • Wound healing

ASJC Scopus subject areas

  • Surgery
  • Dermatology


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