Comparison of two types of xenogeneic matrices to treat single gingival recessions: A randomized clinical trial

Mauro Pedrine Santamaria; Amanda Rossato; Manuela Maria Viana Miguel; Manuela Bafini Fonseca; Cristhian Reynaldo Gomez Bautista; Andrea Carvalho de Marco; Ingrid Fernandes Mathias-Santamaria; Laís Fernanda Ferreira Ferraz

doi:10.1002/JPER.21-0212

Comparison of two types of xenogeneic matrices to treat single gingival recessions: A randomized clinical trial

Mauro Pedrine Santamaria, Amanda Rossato, Manuela Maria Viana Miguel, Manuela Bafini Fonseca, Cristhian Reynaldo Gomez Bautista, Andrea Carvalho de Marco, Ingrid Fernandes Mathias-Santamaria, Laís Fernanda Ferreira Ferraz

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Background: Xenogeneic matrices (XMs) have been increasingly used for root coverage procedures. This study compared the use of two types of XM (collagen matrix [CM] and xenogeneic acellular dermal matrix [XDM]) associated with the coronally advanced flap technique (CAF) to treat single gingival recessions. Methods: Seventy-five patients presenting single RT1 gingival recession were treated by CAF (control group, n = 25), CAF+CM (test group 1, n = 25), or CAF+XDM (test group 2, n = 25) and completed 6-month follow-up. Clinical, patient-centered, and esthetic assessments were performed and intra- and intergroup differences were analyzed. Results: At 6 months, the mean recession reduction for CAF, CAF+CM, and CAF+XDM was 2.4 ± 0.8 mm, 2.4 ± 0.9 mm and 2.1 ± 0.8 mm, respectively (P > 0.05). The corresponding mean percentage of root coverage was 78.9% ± 26.2% for CAF, 78.0% ± 28.5% for CAF+CM, and 65.6% ± 26.9% for CAF+XDM (P > 0.05). Dentin hypersensitivity and esthetic conditions showed significantly improvements in all groups. Test groups presented significant gains in gingival thickness (GT; CAF+CM: 0.4 ± 0.3 mm; CAF+XDM: 0.4 ± 0.2 mm) compared to the control group (CAF: 0.0 ± 0.1 mm; P < 0.05). Conclusion: The CAF, CAF+CM, and CAF+XDM treatments each provided similar results in the treatment of single gingival recessions. The addition of either CM or XDM to CAF increases the GT.

Original language	English
Pages (from-to)	709-720
Number of pages	12
Journal	Journal of Periodontology
Volume	93
Issue number	5
DOIs	https://doi.org/10.1002/JPER.21-0212
State	Published - May 2022

Bibliographical note

Funding Information:
The authors appreciate the financial support provided by Research Funding Agency from São Paulo State (FAPESP), Brazil (grants #2018/03284‐3); Coordination for the Improvement of Higher Education Personnel (CAPES), Brazil – Finance Code 001. Dr. Mauro Santamaria is supported by the National Council for Scientific and Technological Development from Brazil, CNPq (grant # 304269/2019‐0).

Publisher Copyright:
© 2021 American Academy of Periodontology.

Keywords

connective tissue graft(s)
cosmetic periodontal plastic surgery
gingival recession

ASJC Scopus subject areas

Periodontics

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10.1002/JPER.21-0212

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@article{557bc7b1e4a046f899bce06dbd7fe280,

title = "Comparison of two types of xenogeneic matrices to treat single gingival recessions: A randomized clinical trial",

abstract = "Background: Xenogeneic matrices (XMs) have been increasingly used for root coverage procedures. This study compared the use of two types of XM (collagen matrix [CM] and xenogeneic acellular dermal matrix [XDM]) associated with the coronally advanced flap technique (CAF) to treat single gingival recessions. Methods: Seventy-five patients presenting single RT1 gingival recession were treated by CAF (control group, n = 25), CAF+CM (test group 1, n = 25), or CAF+XDM (test group 2, n = 25) and completed 6-month follow-up. Clinical, patient-centered, and esthetic assessments were performed and intra- and intergroup differences were analyzed. Results: At 6 months, the mean recession reduction for CAF, CAF+CM, and CAF+XDM was 2.4 ± 0.8 mm, 2.4 ± 0.9 mm and 2.1 ± 0.8 mm, respectively (P > 0.05). The corresponding mean percentage of root coverage was 78.9% ± 26.2% for CAF, 78.0% ± 28.5% for CAF+CM, and 65.6% ± 26.9% for CAF+XDM (P > 0.05). Dentin hypersensitivity and esthetic conditions showed significantly improvements in all groups. Test groups presented significant gains in gingival thickness (GT; CAF+CM: 0.4 ± 0.3 mm; CAF+XDM: 0.4 ± 0.2 mm) compared to the control group (CAF: 0.0 ± 0.1 mm; P < 0.05). Conclusion: The CAF, CAF+CM, and CAF+XDM treatments each provided similar results in the treatment of single gingival recessions. The addition of either CM or XDM to CAF increases the GT.",

keywords = "connective tissue graft(s), cosmetic periodontal plastic surgery, gingival recession",

author = "Santamaria, {Mauro Pedrine} and Amanda Rossato and Miguel, {Manuela Maria Viana} and Fonseca, {Manuela Bafini} and Bautista, {Cristhian Reynaldo Gomez} and {de Marco}, {Andrea Carvalho} and Mathias-Santamaria, {Ingrid Fernandes} and {Ferreira Ferraz}, {La{\'i}s Fernanda}",

note = "Funding Information: The authors appreciate the financial support provided by Research Funding Agency from S{\~a}o Paulo State (FAPESP), Brazil (grants #2018/03284‐3); Coordination for the Improvement of Higher Education Personnel (CAPES), Brazil – Finance Code 001. Dr. Mauro Santamaria is supported by the National Council for Scientific and Technological Development from Brazil, CNPq (grant # 304269/2019‐0). Publisher Copyright: {\textcopyright} 2021 American Academy of Periodontology.",

year = "2022",

month = may,

doi = "10.1002/JPER.21-0212",

language = "English",

volume = "93",

pages = "709--720",

number = "5",

}

TY - JOUR

T1 - Comparison of two types of xenogeneic matrices to treat single gingival recessions

T2 - A randomized clinical trial

AU - Santamaria, Mauro Pedrine

AU - Rossato, Amanda

AU - Miguel, Manuela Maria Viana

AU - Fonseca, Manuela Bafini

AU - Bautista, Cristhian Reynaldo Gomez

AU - de Marco, Andrea Carvalho

AU - Mathias-Santamaria, Ingrid Fernandes

AU - Ferreira Ferraz, Laís Fernanda

N1 - Funding Information: The authors appreciate the financial support provided by Research Funding Agency from São Paulo State (FAPESP), Brazil (grants #2018/03284‐3); Coordination for the Improvement of Higher Education Personnel (CAPES), Brazil – Finance Code 001. Dr. Mauro Santamaria is supported by the National Council for Scientific and Technological Development from Brazil, CNPq (grant # 304269/2019‐0). Publisher Copyright: © 2021 American Academy of Periodontology.

PY - 2022/5

Y1 - 2022/5

N2 - Background: Xenogeneic matrices (XMs) have been increasingly used for root coverage procedures. This study compared the use of two types of XM (collagen matrix [CM] and xenogeneic acellular dermal matrix [XDM]) associated with the coronally advanced flap technique (CAF) to treat single gingival recessions. Methods: Seventy-five patients presenting single RT1 gingival recession were treated by CAF (control group, n = 25), CAF+CM (test group 1, n = 25), or CAF+XDM (test group 2, n = 25) and completed 6-month follow-up. Clinical, patient-centered, and esthetic assessments were performed and intra- and intergroup differences were analyzed. Results: At 6 months, the mean recession reduction for CAF, CAF+CM, and CAF+XDM was 2.4 ± 0.8 mm, 2.4 ± 0.9 mm and 2.1 ± 0.8 mm, respectively (P > 0.05). The corresponding mean percentage of root coverage was 78.9% ± 26.2% for CAF, 78.0% ± 28.5% for CAF+CM, and 65.6% ± 26.9% for CAF+XDM (P > 0.05). Dentin hypersensitivity and esthetic conditions showed significantly improvements in all groups. Test groups presented significant gains in gingival thickness (GT; CAF+CM: 0.4 ± 0.3 mm; CAF+XDM: 0.4 ± 0.2 mm) compared to the control group (CAF: 0.0 ± 0.1 mm; P < 0.05). Conclusion: The CAF, CAF+CM, and CAF+XDM treatments each provided similar results in the treatment of single gingival recessions. The addition of either CM or XDM to CAF increases the GT.

AB - Background: Xenogeneic matrices (XMs) have been increasingly used for root coverage procedures. This study compared the use of two types of XM (collagen matrix [CM] and xenogeneic acellular dermal matrix [XDM]) associated with the coronally advanced flap technique (CAF) to treat single gingival recessions. Methods: Seventy-five patients presenting single RT1 gingival recession were treated by CAF (control group, n = 25), CAF+CM (test group 1, n = 25), or CAF+XDM (test group 2, n = 25) and completed 6-month follow-up. Clinical, patient-centered, and esthetic assessments were performed and intra- and intergroup differences were analyzed. Results: At 6 months, the mean recession reduction for CAF, CAF+CM, and CAF+XDM was 2.4 ± 0.8 mm, 2.4 ± 0.9 mm and 2.1 ± 0.8 mm, respectively (P > 0.05). The corresponding mean percentage of root coverage was 78.9% ± 26.2% for CAF, 78.0% ± 28.5% for CAF+CM, and 65.6% ± 26.9% for CAF+XDM (P > 0.05). Dentin hypersensitivity and esthetic conditions showed significantly improvements in all groups. Test groups presented significant gains in gingival thickness (GT; CAF+CM: 0.4 ± 0.3 mm; CAF+XDM: 0.4 ± 0.2 mm) compared to the control group (CAF: 0.0 ± 0.1 mm; P < 0.05). Conclusion: The CAF, CAF+CM, and CAF+XDM treatments each provided similar results in the treatment of single gingival recessions. The addition of either CM or XDM to CAF increases the GT.

KW - connective tissue graft(s)

KW - cosmetic periodontal plastic surgery

KW - gingival recession

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DO - 10.1002/JPER.21-0212

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SN - 0022-3492

VL - 93

SP - 709

EP - 720

JO - Journal of Periodontology

JF - Journal of Periodontology

IS - 5

ER -

Comparison of two types of xenogeneic matrices to treat single gingival recessions: A randomized clinical trial

Abstract

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Keywords

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