TY - JOUR
T1 - Complementary neural mechanisms for tracking items in human working memory
AU - Jiang, Yang
AU - Haxby, James V.
AU - Martin, Alex
AU - Ungerleider, Leslie G.
AU - Parasuraman, Raja
PY - 2000/1/28
Y1 - 2000/1/28
N2 - Recognition of a specific visual target among equally familiar distracters requires neural mechanisms for tracking items in working memory. Event-related functional magnetic resonance imaging revealed evidence for two such mechanisms: (i) Enhanced neural responses, primarily in the frontal cortex, were associated with the target and were maintained across repetitions of the target (ii) Reduced responses, primarily in the extrastriate visual cortex, were associated with stimulus repetition, regardless of whether the stimulus was a target or a distracter. These complementary neural mechanisms track the status of familiar items in working memory, allowing for the efficient recognition of a currently relevant object and rejection of irrelevant distracters.
AB - Recognition of a specific visual target among equally familiar distracters requires neural mechanisms for tracking items in working memory. Event-related functional magnetic resonance imaging revealed evidence for two such mechanisms: (i) Enhanced neural responses, primarily in the frontal cortex, were associated with the target and were maintained across repetitions of the target (ii) Reduced responses, primarily in the extrastriate visual cortex, were associated with stimulus repetition, regardless of whether the stimulus was a target or a distracter. These complementary neural mechanisms track the status of familiar items in working memory, allowing for the efficient recognition of a currently relevant object and rejection of irrelevant distracters.
UR - http://www.scopus.com/inward/record.url?scp=0034723225&partnerID=8YFLogxK
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U2 - 10.1126/science.287.5453.643
DO - 10.1126/science.287.5453.643
M3 - Article
C2 - 10649996
AN - SCOPUS:0034723225
SN - 0036-8075
VL - 287
SP - 643
EP - 646
JO - Science
JF - Science
IS - 5453
ER -