Complications of Chronic Pancreatitis

Mitchell L. Ramsey, Darwin L. Conwell, Phil A. Hart

Research output: Contribution to journalReview articlepeer-review

63 Scopus citations

Abstract

Chronic pancreatitis is a disease that leads to irreversible changes in the pancreatic morphology and function. The loss of function can lead to diabetes mellitus and exocrine pancreatic insufficiency. The inflammation and fibrosis can also lead to other complications including a chronic abdominal pain syndrome, metabolic bone disease, and pancretic cancer. This article reviews our current understanding of the mechanisms and management of these complications of chronic pancreatitis.

Original languageEnglish
Pages (from-to)1745-1750
Number of pages6
JournalDigestive Diseases and Sciences
Volume62
Issue number7
DOIs
StatePublished - Jul 1 2017

Bibliographical note

Funding Information:
Research reported in this publication was supported by the National Cancer Institute and National Institute of Diabetes And Digestive and Kidney Diseases (NIDDK) under Award Number U01DK108327 (PH, DC). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

Publisher Copyright:
© 2017, Springer Science+Business Media New York.

Keywords

  • Pancreatic cancer
  • Pancreatic pseudocyst
  • Pancreatogenic diabetes
  • Splenic vein thrombus
  • Type 3c diabetes mellitus

ASJC Scopus subject areas

  • Physiology
  • Gastroenterology

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