TY - JOUR
T1 - Conference overview
T2 - Molecular mechanisms of metal toxicity and carcinogenesis
AU - Bower, Jacquelyn J.
AU - Leonard, Stephen S.
AU - Shi, Xianglin
PY - 2005/11
Y1 - 2005/11
N2 - Chronic exposure to many heavy metals and metal-derivatives is associated with an increased risk of cancer, although the mechanisms of tumorigenesis are largely unknown. Approximately 125 scientists attended the 3rd Conference on Molecular Mechanisms of Metal Toxicity and Carcinogenesis and presented the latest research concerning these mechanisms. Major areas of focus included exposure assessment and biomarker identification, roles of ROS and antioxidants in carcinogenesis, mechanisms of metal-induced DNA damage, metal signalling, and the development of animal models for use in metal toxicology studies. Here we highlight some of the research presented, and summarize the conference proceedings.
AB - Chronic exposure to many heavy metals and metal-derivatives is associated with an increased risk of cancer, although the mechanisms of tumorigenesis are largely unknown. Approximately 125 scientists attended the 3rd Conference on Molecular Mechanisms of Metal Toxicity and Carcinogenesis and presented the latest research concerning these mechanisms. Major areas of focus included exposure assessment and biomarker identification, roles of ROS and antioxidants in carcinogenesis, mechanisms of metal-induced DNA damage, metal signalling, and the development of animal models for use in metal toxicology studies. Here we highlight some of the research presented, and summarize the conference proceedings.
KW - Antioxidants
KW - Carcinogenesis
KW - DNA damage
KW - Metals
KW - Reactive oxygen species
UR - http://www.scopus.com/inward/record.url?scp=30344458490&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=30344458490&partnerID=8YFLogxK
U2 - 10.1007/s11010-005-8210-7
DO - 10.1007/s11010-005-8210-7
M3 - Review article
C2 - 16283510
AN - SCOPUS:30344458490
SN - 0300-8177
VL - 279
SP - 3
EP - 15
JO - Molecular and Cellular Biochemistry
JF - Molecular and Cellular Biochemistry
IS - 1-2
ER -
