Conformal ceramic electrodes that record glutamate release and corresponding neural activity in primate prefrontal cortex

Robert E. Hampson; Joshua L. Fuqua; Peter F. Huettl; Ioan Opris; Dong Song; Dae Shin; Vasilis Z. Marmarelis; Theodore W. Berger; Greg A. Gerhardt; Sam A. Deadwyler

doi:10.1109/EMBC.2013.6610908

Conformal ceramic electrodes that record glutamate release and corresponding neural activity in primate prefrontal cortex

Robert E. Hampson, Joshua L. Fuqua, Peter F. Huettl, Ioan Opris, Dong Song, Dae Shin, Vasilis Z. Marmarelis, Theodore W. Berger, Greg A. Gerhardt, Sam A. Deadwyler

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

3 Scopus citations

Abstract

Conformal ceramic electrodes utilized in prior recordings of nonhuman primate prefrontal cortical layer 2/3 and layer 5 neurons were used in this study to record tonic glutamate concentration and transient release in layer 2/3 PFC. Tonic glutamate concentration increased in the Match (decision) phase of a visual delayed-match-to-sample (DMS) task, while increased transient glutamate release occurred in the Sample (encoding) phase of the task. Further, spatial vs. object-oriented DMS trials evoked differential changes in glutamate concentration. Thus the same conformal recording electrodes were capable of electrophysiological and electrochemical recording, and revealed similar evidence of neural processing in layers 2/3 and layer 5 during cognitive processing in a behavioral task.

Original language	English
Title of host publication	2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
Pages	5954-5957
Number of pages	4
DOIs	https://doi.org/10.1109/EMBC.2013.6610908
State	Published - 2013
Event	2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013 - Osaka, Japan Duration: Jul 3 2013 → Jul 7 2013

Publication series

Name	Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
ISSN (Print)	1557-170X

Conference

Conference	2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
Country/Territory	Japan
City	Osaka
Period	7/3/13 → 7/7/13

Funding

Funders	Funder number
National Institute of Biomedical Imaging and Bioengineering	P41EB001978

ASJC Scopus subject areas

Signal Processing
Biomedical Engineering
Computer Vision and Pattern Recognition
Health Informatics

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10.1109/EMBC.2013.6610908

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Hampson, R. E., Fuqua, J. L., Huettl, P. F., Opris, I., Song, D., Shin, D., Marmarelis, V. Z., Berger, T. W., Gerhardt, G. A., & Deadwyler, S. A. (2013). Conformal ceramic electrodes that record glutamate release and corresponding neural activity in primate prefrontal cortex. In 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013 (pp. 5954-5957). Article 6610908 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). https://doi.org/10.1109/EMBC.2013.6610908

Hampson, Robert E. ; Fuqua, Joshua L. ; Huettl, Peter F. et al. / Conformal ceramic electrodes that record glutamate release and corresponding neural activity in primate prefrontal cortex. 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013. 2013. pp. 5954-5957 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).

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title = "Conformal ceramic electrodes that record glutamate release and corresponding neural activity in primate prefrontal cortex",

abstract = "Conformal ceramic electrodes utilized in prior recordings of nonhuman primate prefrontal cortical layer 2/3 and layer 5 neurons were used in this study to record tonic glutamate concentration and transient release in layer 2/3 PFC. Tonic glutamate concentration increased in the Match (decision) phase of a visual delayed-match-to-sample (DMS) task, while increased transient glutamate release occurred in the Sample (encoding) phase of the task. Further, spatial vs. object-oriented DMS trials evoked differential changes in glutamate concentration. Thus the same conformal recording electrodes were capable of electrophysiological and electrochemical recording, and revealed similar evidence of neural processing in layers 2/3 and layer 5 during cognitive processing in a behavioral task.",

author = "Hampson, {Robert E.} and Fuqua, {Joshua L.} and Huettl, {Peter F.} and Ioan Opris and Dong Song and Dae Shin and Marmarelis, {Vasilis Z.} and Berger, {Theodore W.} and Gerhardt, {Greg A.} and Deadwyler, {Sam A.}",

year = "2013",

doi = "10.1109/EMBC.2013.6610908",

language = "English",

isbn = "9781457702167",

series = "Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS",

pages = "5954--5957",

booktitle = "2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013",

note = "2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013 ; Conference date: 03-07-2013 Through 07-07-2013",

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Hampson, RE, Fuqua, JL, Huettl, PF, Opris, I, Song, D, Shin, D, Marmarelis, VZ, Berger, TW, Gerhardt, GA & Deadwyler, SA 2013, Conformal ceramic electrodes that record glutamate release and corresponding neural activity in primate prefrontal cortex. in 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013., 6610908, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, pp. 5954-5957, 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013, Osaka, Japan, 7/3/13. https://doi.org/10.1109/EMBC.2013.6610908

Conformal ceramic electrodes that record glutamate release and corresponding neural activity in primate prefrontal cortex. / Hampson, Robert E.; Fuqua, Joshua L.; Huettl, Peter F. et al.
2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013. 2013. p. 5954-5957 6610908 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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AU - Hampson, Robert E.

AU - Fuqua, Joshua L.

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AU - Song, Dong

AU - Shin, Dae

AU - Marmarelis, Vasilis Z.

AU - Berger, Theodore W.

AU - Gerhardt, Greg A.

AU - Deadwyler, Sam A.

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AB - Conformal ceramic electrodes utilized in prior recordings of nonhuman primate prefrontal cortical layer 2/3 and layer 5 neurons were used in this study to record tonic glutamate concentration and transient release in layer 2/3 PFC. Tonic glutamate concentration increased in the Match (decision) phase of a visual delayed-match-to-sample (DMS) task, while increased transient glutamate release occurred in the Sample (encoding) phase of the task. Further, spatial vs. object-oriented DMS trials evoked differential changes in glutamate concentration. Thus the same conformal recording electrodes were capable of electrophysiological and electrochemical recording, and revealed similar evidence of neural processing in layers 2/3 and layer 5 during cognitive processing in a behavioral task.

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Hampson RE, Fuqua JL, Huettl PF, Opris I, Song D, Shin D et al. Conformal ceramic electrodes that record glutamate release and corresponding neural activity in primate prefrontal cortex. In 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013. 2013. p. 5954-5957. 6610908. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). doi: 10.1109/EMBC.2013.6610908

Conformal ceramic electrodes that record glutamate release and corresponding neural activity in primate prefrontal cortex

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