Congenital Ocular Motor Apraxia: A Possible Disconnection Syndrome

William W. Orrison, William C. Robertson

Research output: Contribution to journalArticlepeer-review

39 Scopus citations


In 1952, Cogan introduced the term “congenital ocular motor apraxia” (COA) to describe an abnormality of eye movements characterized by absent or defective voluntary horizontal gaze. Since his original description, there have been few subsequent reports of this disorder. A ten-year review of clinical records from the University of Wisconsin Hospitals disclosed eight patients with COA. In two patients subjected to neuroradiologic testing, agenesis of the corpus callosum was detected. Voluntary horizontal gaze appears to be a learned phenomenon, and defective interhemispheric transfer of visual information may be important in the pathogenesis of COA.

Original languageEnglish
Pages (from-to)29-31
Number of pages3
JournalArchives of Neurology
Issue number1
StatePublished - Jan 1979

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology


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