Connective tissue graft plus resin-modified glass ionomer restoration for the treatment of gingival recession associated with non-carious cervical lesions: Microbiological and immunological results

Mauro Pedrine Santamaria, Marcio Zaffalon Casati, Francisco Humberto Nociti, Antônio Wilson Sallum, Enilson Antônio Sallum, Ikramuddin Aukhil, Shannon Margaret Wallet, Luciana Machion Shaddox

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

Objectives: It was previously reported the clinical results of placing subgingival resin-modified glass ionomer restoration for treatment of gingival recession associated with non-carious cervical lesions. The aim of this study was to evaluate the influence of this treatment on the subgingival biofilm and gingival crevicular fluid (GCF) inflammatory markers. Materials and methods: Thirty-four patients presenting the combined defect were selected. The defects were treated with either connective tissue graft plus modified glass ionomer restoration (CTG+R) or with connective tissue graft only (CTG). Evaluation included bleeding on probing and probing depth, 5 different bacteria targets in the subgingival plaque assessed at baseline, 45, and 180 days post treatments, and 9 inflammatory mediators were also assessed in the GCF. Results: The levels of each target bacterium were similar during the entire period of evaluation (p > 0. 05), both within and between groups. The highest levels among the studied species were observed for the bacterium associated with periodontal health. Additionally, the levels of all cyto/chemokines analyzed were not statistically different between groups (p > 0. 05). Conclusion: Within the limits of the present study, it can be concluded that the presence of subgingival restoration may not interfere with the subgingival microflora and with GCF inflammatory markers analyzed. Clinical relevance: This approach usually leads to the placement of a subgingival restoration. There is a lack of information about the microbiological and immunological effects of this procedure. The results suggest that this combined approach may be considered as a treatment option for the lesion included in this study.

Original languageEnglish
Pages (from-to)67-77
Number of pages11
JournalClinical Oral Investigations
Volume17
Issue number1
DOIs
StatePublished - Jan 2013

Bibliographical note

Funding Information:
report no conflicts of interest related to this study. The study was funded by the authors. The authors would like to thank the Foundation for the Development of Personnel in Higher Education (CAPES) and the São Paulo Foundation for Research (FAPESP; 09/17194-7) for supporting Dr. Mauro P. Santamaria. Dr. Enilson A. Sallum would like to thank the support of CNPQ (#300817/2007-0).

Keywords

  • Cementoenamel junction
  • Gingival recession/surgery
  • Glass ionomer cement
  • Surgical flap
  • Tooth abrasion

ASJC Scopus subject areas

  • Dentistry (all)

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