Contribution of previable births to infant mortality rate racial disparity in the United States

MacKenzie K. Lee; Eric S. Hall; Emily DeFranco

doi:10.1038/s41372-019-0394-x

Contribution of previable births to infant mortality rate racial disparity in the United States

MacKenzie K. Lee
, Eric S. Hall
, Emily DeFranco

Obstetrics and Gynecology

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Objective: To quantify racial differences in contribution of previable live births (<20 weeks gestational age (GA)) to United States (US) Infant Mortality Rates (IMR). Methods: Population-based retrospective cohort of US live births (2007–14) using CDC WONDER database stratified by maternal race/ethnicity. We compared the contribution of previable births to IMR and calculated modified IMRs (≥20 weeks GA) excluding previable live births in each group. Contingency tables and chi-square calculations were performed to detect differences between groups. Results: Previable deaths represented 4.1%, 7.7%, and 5.0% of total deaths for nonHispanic white, nonHispanic black, and Hispanic, respectively. Previable contribution to total IMR are 0.21, 0.89, and 0.26 per 1000 live births (P < 0.0001). Modified IMRs are 4.98, 10.85, and 4.69 deaths per 1000 live births. Conclusion: IMR standardization with a minimum GA may obscure the disproportionate contribution of previable births to IMRs among the black population, which has the largest proportion of previable births.

Original language	English
Pages (from-to)	1190-1195
Number of pages	6
Journal	Journal of Perinatology
Volume	39
Issue number	9
DOIs	https://doi.org/10.1038/s41372-019-0394-x
State	Published - Sep 1 2019

Bibliographical note

Publisher Copyright:
© 2019, Springer Nature America, Inc.

Funding

Funding ML received research funding from an educational grant from the University of Cincinnati, Department of Obstetrics and Gynecology Women’s Health Scholars Program at the University of Cincinnati College of Medicine. ED received research funding from the Perinatal Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio; March of Dimes Prematurity Research Center Ohio Collaborative

Funders	Funder number
Department of Obstetrics and Gynecology Women’s Health Scholars Program
Perinatal Institute
March of Dimes Research Foundation	22-FY14-470
Cincinnati Children's Hospital Medical Center
University of Cincinnati University Research Council
March of Dimes Prematurity Research Center Ohio Collaborative
University of Cincinnati College of Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Obstetrics and Gynecology

Access to Document

10.1038/s41372-019-0394-x

Cite this

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title = "Contribution of previable births to infant mortality rate racial disparity in the United States",

abstract = "Objective: To quantify racial differences in contribution of previable live births (<20 weeks gestational age (GA)) to United States (US) Infant Mortality Rates (IMR). Methods: Population-based retrospective cohort of US live births (2007–14) using CDC WONDER database stratified by maternal race/ethnicity. We compared the contribution of previable births to IMR and calculated modified IMRs (≥20 weeks GA) excluding previable live births in each group. Contingency tables and chi-square calculations were performed to detect differences between groups. Results: Previable deaths represented 4.1\%, 7.7\%, and 5.0\% of total deaths for nonHispanic white, nonHispanic black, and Hispanic, respectively. Previable contribution to total IMR are 0.21, 0.89, and 0.26 per 1000 live births (P < 0.0001). Modified IMRs are 4.98, 10.85, and 4.69 deaths per 1000 live births. Conclusion: IMR standardization with a minimum GA may obscure the disproportionate contribution of previable births to IMRs among the black population, which has the largest proportion of previable births.",

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N2 - Objective: To quantify racial differences in contribution of previable live births (<20 weeks gestational age (GA)) to United States (US) Infant Mortality Rates (IMR). Methods: Population-based retrospective cohort of US live births (2007–14) using CDC WONDER database stratified by maternal race/ethnicity. We compared the contribution of previable births to IMR and calculated modified IMRs (≥20 weeks GA) excluding previable live births in each group. Contingency tables and chi-square calculations were performed to detect differences between groups. Results: Previable deaths represented 4.1%, 7.7%, and 5.0% of total deaths for nonHispanic white, nonHispanic black, and Hispanic, respectively. Previable contribution to total IMR are 0.21, 0.89, and 0.26 per 1000 live births (P < 0.0001). Modified IMRs are 4.98, 10.85, and 4.69 deaths per 1000 live births. Conclusion: IMR standardization with a minimum GA may obscure the disproportionate contribution of previable births to IMRs among the black population, which has the largest proportion of previable births.

AB - Objective: To quantify racial differences in contribution of previable live births (<20 weeks gestational age (GA)) to United States (US) Infant Mortality Rates (IMR). Methods: Population-based retrospective cohort of US live births (2007–14) using CDC WONDER database stratified by maternal race/ethnicity. We compared the contribution of previable births to IMR and calculated modified IMRs (≥20 weeks GA) excluding previable live births in each group. Contingency tables and chi-square calculations were performed to detect differences between groups. Results: Previable deaths represented 4.1%, 7.7%, and 5.0% of total deaths for nonHispanic white, nonHispanic black, and Hispanic, respectively. Previable contribution to total IMR are 0.21, 0.89, and 0.26 per 1000 live births (P < 0.0001). Modified IMRs are 4.98, 10.85, and 4.69 deaths per 1000 live births. Conclusion: IMR standardization with a minimum GA may obscure the disproportionate contribution of previable births to IMRs among the black population, which has the largest proportion of previable births.

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Contribution of previable births to infant mortality rate racial disparity in the United States

Abstract

Bibliographical note

Funding

UN SDGs

ASJC Scopus subject areas

Access to Document

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Cite this