Correlates of fatigue in patients with heart failure

Lorraine S. Evangelista, Debra K. Moser, Cheryl Westlake, Nancy Pike, Alvina Ter-Galstanyan, Kathleen Dracup

Research output: Contribution to journalArticlepeer-review

70 Scopus citations


This study was conducted to determine the prevalence of fatigue and identify its demographic, clinical, and psychological correlates in 150 heart failure (HF) patients (73% men, 66% Caucasian, mean age 55.0 years, mean ejection fraction 26.7%±11%), from a single HF center, using the Profile of Mood States-Fatigue Subscale, the Minnesota Living With Heart Failure Questionnaire, and the Beck Depression Inventory. Sociodemographic and clinical data were obtained through self-report and chart abstraction. High levels of fatigue were reported in 50.4% of men and 51.2% of women. In a multivariate model, maximal workload, physical health, emotional health, and depression explained 51% of the variance in fatigue (P<.001). Fatigue in patients with HF is associated with both clinical and psychosocial variables, offering a number of targets for intervention. These findings suggest the need for multiple risk factor intervention strategies that improve physical and emotional health to decrease fatigue. Patients with depression warrant particular scrutiny.

Original languageEnglish
Pages (from-to)12-17
Number of pages6
JournalProgress in Cardiovascular Nursing
Issue number1
StatePublished - 2008

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Nursing (miscellaneous)


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