Abstract
A near infrared reflectometer was fabricated with a laser (820 nm) diode and a photodiode detector circuit. Because the isosbestic point of HbO2 and Hb is approximately 810 nm, change in the reflected near infrared signal is approximately proportional to change of blood volume. With this instrument, recordings of local change of cerebral blood volume were obtained lateral to and along the sagittal sinus of piglets. Intracranial pressure was also recorded. A correlation analysis was employed to evaluate the strength of similarity between change in cerebral blood volume and change in intracranial pressure. During normal vascular tone, local changes of cerebral blood volume were found to have a high correlation with intracranial pressure. During loss of vascular tone, the two signals were found to be uncorrelated.
| Original language | English |
|---|---|
| Pages (from-to) | 1750-1751 |
| Number of pages | 2 |
| Journal | Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings |
| Volume | 4 |
| State | Published - 1996 |
| Event | Proceedings of the 1996 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Part 4 (of 5) - Amsterdam, Neth Duration: Oct 31 1996 → Nov 3 1996 |
ASJC Scopus subject areas
- Signal Processing
- Biomedical Engineering
- Computer Vision and Pattern Recognition
- Health Informatics