Corrigendum to “microRNA-1 regulates metabolic flexibility by programming skeletal muscle pyruvate metabolism” [Mol Metabol 98 (2025) 1–23/102182] (Molecular Metabolism (2025) 98, (S2212877825000894), (10.1016/j.molmet.2025.102182))

Ahmed Ismaeel, Bailey D. Peck, McLane M. Montgomery, Benjamin I. Burke, Jensen Goh, Abigail B. Franco, Qin Xia, Katarzyna Goljanek-Whysall, Brian McDonagh, Jared M. McLendon, Pieter J. Koopmans, Daniel Jacko, Kirill Schaaf, Wilhelm Bloch, Sebastian Gehlert, Kevin A. Murach, Kelsey H. Fisher-Wellman, Ryan L. Boudreau, Yuan Wen, John J. McCarthy

Research output: Contribution to journalComment/debate

Abstract

The authors regret the inadvertent publication of links to a website to query AGO2 eCLIP-seq data (http://www.mir-engagemint.io/) and UCSC Genome Browser (https://genome.ucsc.edu/s/bdpeck/Ago2%20eCLIP). These links have been inactivated. The authors would like to apologise for any inconvenience caused.

Original languageEnglish
Article number102223
JournalMolecular Metabolism
Volume100
DOIs
StatePublished - Oct 2025

Bibliographical note

Publisher Copyright:
© 2025 The Author(s)

Funding

We thank Marsha Ensor and the University of Kentucky (UK) Energy Balance and Body Composition core for the calorimetry expertise. The UK Energy Balance and Body Composition core facility is supported in part by the Office of the Vice President for Research and the UK College of Medicine. Mass spectrometric analysis was performed at the University of Kentucky Mass Spectrometry and Proteomics Core facility and is supported in part by the Office of the Vice President for Research. We thank Djamel Lebeche, PhD, formerly of the Cardiovascular Institute, Icahn School of Medicine at Mount Sinai and currently at the University of Tennessee Health Science Center, for helping us re-derive the miR-1 floxed mice. Special thanks to Dr. Charlotte A. Peterson for the excellent insights and feedback. This work was supported by National Institutes of Health grants from the National Institute on Aging ( R01AG069909 to J.J.M. and R00AG063994 to K.A.M.) and the National Heart, Lung and Blood Institute ( HL144717 and HL150557 to R.L.B.). C. elegans were cultured on NGM plates seeded with E. Coli (OP50) at 20 °C. N2 (Bristol strain, wild type) and mir-1 mutant MT17810 [mir-1(n4102) I] strains were obtained from Caenorhabditis Genetics Center (CGC), supported by the National Institutes of Health - Office of Research Infrastructure Programs (P40 OD010440). Swimming exercise was performed according to previous descriptions [ 22 ]. Synchronized worms were bleached by sodium hydroxide bleaching buffer, then incubated overnight in M9 buffer on a rocker at 20 °C. Larval stage L1 worm populations were transferred to 60 mm NGM plates seeded with OP50 for 2 days to obtain adult D1 worms, which were then washed off plates with 3 ml M9 buffer and allowed to settle under gravity, with the supernatant including OP50 and larvae removed, for a total of 3 times. Worms were then transferred to unseeded NGM plates with M9 buffer using a glass Pasteur pipette, and all plates were then moved to a 20 °C incubator for 90 min. After swimming exercise, worms were washed off with M9 buffer, gravity settled, and transferred to new 60 mm NGM plates seeded with OP50 in a 20 °C incubator. Swimming exercise was performed 2 × 90 min daily for 5 days.

FundersFunder number
UK College of Medicine
Office of the Vice President for Research
National Institute on AgingR00AG063994, R01AG069909
National Heart, Lung, and Blood Institute (NHLBI)HL144717, HL150557
National Institutes of Health (NIH)P40 OD010440

    ASJC Scopus subject areas

    • Molecular Biology
    • Cell Biology

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