COVID-19 and biomarkers of thrombosis: focus on von Willebrand factor and extracellular vesicles

doi:10.1007/s11239-021-02544-x

COVID-19 and biomarkers of thrombosis: focus on von Willebrand factor and extracellular vesicles

Internal Medicine

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

COVID-19, caused by the SARS-CoV-2 virus, is responsible for a pandemic of unparalleled portion over the past century. While the acute phase of infection causes significant morbidity and mortality, post-acute sequelae that can affect essentially any organ system is rapidly taking on an equally large part of the overall impact on human health, quality of life, attempts to return to normalcy and the global economy. Herein, we summarize the potential role of von Willebrand Factor and extracellular vesicles toward understanding the pathophysiology, clinical presentation, duration of illness, diagnostic approach and management of COVID-19 and its sequelae.

Original language	English
Pages (from-to)	1010-1019
Number of pages	10
Journal	Journal of Thrombosis and Thrombolysis
Volume	52
Issue number	4
DOIs	https://doi.org/10.1007/s11239-021-02544-x
State	Published - Nov 2021

Bibliographical note

Publisher Copyright:
© 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

Keywords

Biomarkers
COVID-19
Thrombosis
von Willebrand factor

ASJC Scopus subject areas

Hematology
Cardiology and Cardiovascular Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1007/s11239-021-02544-x

Cite this

@article{7bc28599b08045d98f7da071e2e6c312,

title = "COVID-19 and biomarkers of thrombosis: focus on von Willebrand factor and extracellular vesicles",

abstract = "COVID-19, caused by the SARS-CoV-2 virus, is responsible for a pandemic of unparalleled portion over the past century. While the acute phase of infection causes significant morbidity and mortality, post-acute sequelae that can affect essentially any organ system is rapidly taking on an equally large part of the overall impact on human health, quality of life, attempts to return to normalcy and the global economy. Herein, we summarize the potential role of von Willebrand Factor and extracellular vesicles toward understanding the pathophysiology, clinical presentation, duration of illness, diagnostic approach and management of COVID-19 and its sequelae.",

keywords = "Biomarkers, COVID-19, Thrombosis, von Willebrand factor",

author = "Becker, {Richard C.} and Travis Sexton and Susan Smyth",

note = "Publisher Copyright: {\textcopyright} 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.",

year = "2021",

month = nov,

doi = "10.1007/s11239-021-02544-x",

language = "English",

volume = "52",

pages = "1010--1019",

number = "4",

}

TY - JOUR

T1 - COVID-19 and biomarkers of thrombosis

T2 - focus on von Willebrand factor and extracellular vesicles

AU - Becker, Richard C.

AU - Sexton, Travis

AU - Smyth, Susan

PY - 2021/11

Y1 - 2021/11

N2 - COVID-19, caused by the SARS-CoV-2 virus, is responsible for a pandemic of unparalleled portion over the past century. While the acute phase of infection causes significant morbidity and mortality, post-acute sequelae that can affect essentially any organ system is rapidly taking on an equally large part of the overall impact on human health, quality of life, attempts to return to normalcy and the global economy. Herein, we summarize the potential role of von Willebrand Factor and extracellular vesicles toward understanding the pathophysiology, clinical presentation, duration of illness, diagnostic approach and management of COVID-19 and its sequelae.

AB - COVID-19, caused by the SARS-CoV-2 virus, is responsible for a pandemic of unparalleled portion over the past century. While the acute phase of infection causes significant morbidity and mortality, post-acute sequelae that can affect essentially any organ system is rapidly taking on an equally large part of the overall impact on human health, quality of life, attempts to return to normalcy and the global economy. Herein, we summarize the potential role of von Willebrand Factor and extracellular vesicles toward understanding the pathophysiology, clinical presentation, duration of illness, diagnostic approach and management of COVID-19 and its sequelae.

KW - Biomarkers

KW - COVID-19

KW - Thrombosis

KW - von Willebrand factor

UR - http://www.scopus.com/inward/record.url?scp=85112623391&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85112623391&partnerID=8YFLogxK

U2 - 10.1007/s11239-021-02544-x

DO - 10.1007/s11239-021-02544-x

M3 - Article

C2 - 34350541

AN - SCOPUS:85112623391

SN - 0929-5305

VL - 52

SP - 1010

EP - 1019

JO - Journal of Thrombosis and Thrombolysis

JF - Journal of Thrombosis and Thrombolysis

IS - 4

ER -

COVID-19 and biomarkers of thrombosis: focus on von Willebrand factor and extracellular vesicles

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this