Abstract
INTRODUCTION: Behavioral and psychiatric symptoms of dementia (BPSDs) and functional impairment have a major impact on quality of life for people living with dementia (PLWD). Development of caregiver-initiated interventions, including environmental assessment and modification, are priorities in the field. METHODS: An open-label study of 40 caregivers of PLWD with BPSDs that underwent a 6-week telehealth person-environment intervention, Harmony at HOME, was conducted. Feasibility was assessed by improved caregiver mastery. RESULTS: Twenty-eight caregivers completed the intervention, which increased caregiver mastery and decreased stress and burden. There were statistically significant improvements in functional performance of the person living with dementia (p < 0.005) and caregivers’ satisfaction with the person living with dementia's functional performance (p < 0.001). DISCUSSION: The intervention increased caregivers’ skills and knowledge in assessing and modifying the environment to address BPSDs. Although overall caregiver mastery was not changed significantly, additional clinical research assessing caregiver mastery in relation to specific caregiving tasks within the home environment is needed. CLINICAL TRIAL REGISTRATION: Clinicaltrials.gov NCT05202223. Highlights: Aging in place is difficult to achieve for individuals with dementia. A novel dyadic care intervention, Harmony at HOME, improved caregiver outcomes. Future care research should explore performance-based patient outcomes.
| Original language | English |
|---|---|
| Article number | e70405 |
| Journal | Alzheimer's and Dementia |
| Volume | 21 |
| Issue number | 7 |
| DOIs | |
| State | Published - Jul 2025 |
Bibliographical note
Publisher Copyright:© 2025 The Author(s). Alzheimer's & Dementia published by Wiley Periodicals LLC on behalf of Alzheimer's Association.
Funding
The authors thank all the study volunteers. The authors acknowledge Drs. Kenneth Hepburn and Molly Perkins for their guidance in researching concepts of caregiver mastery. The researchers would also like to acknowledge the Institute on Methods and Protocols for Advancement of Clinical Trials in ADRD (IMPACT AD) program for helping develop the intervention used in this study (National Institutes of Health [NIH]/National Institute on Aging [NIA] U13 AG067696 and Alzheimer's Association SG-20-693774). The project described was funded by NIH/NIA P30AG064200 pilot grant and implementation was supported by NIH/NIA P30AG028383. In addition, the first author is supported by NIH/NIA K23AG075262. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. The authors thank all the study volunteers. The authors acknowledge Drs. Kenneth Hepburn and Molly Perkins for their guidance in researching concepts of caregiver mastery. The researchers would also like to acknowledge the Institute on Methods and Protocols for Advancement of Clinical Trials in ADRD (IMPACT AD) program for helping develop the intervention used in this study (National Institutes of Health [NIH]/National Institute on Aging [NIA] U13 AG067696 and Alzheimer's Association SG‐20‐693774). The project described was funded by NIH/NIA P30AG064200 pilot grant and implementation was supported by NIH/NIA P30AG028383. In addition, the first author is supported by NIH/NIA K23AG075262. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH.
| Funders | Funder number |
|---|---|
| National Institutes of Health (NIH) | |
| ADRD | |
| National Institute on Aging | U13 AG067696, P30AG028383, P30AG064200, K23AG075262 |
| Alzheimer's Association | P30AG028383, SG-20-693774, P30AG064200, K23AG075262 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- behavioral and psychiatric symptoms of dementia
- caregiver mastery
- environmental cueing
- non-pharmacological intervention
- occupational therapy
- person–environment fit
- telehealth
ASJC Scopus subject areas
- Epidemiology
- Health Policy
- Developmental Neuroscience
- Clinical Neurology
- Geriatrics and Gerontology
- Cellular and Molecular Neuroscience
- Psychiatry and Mental health
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