Critical review: Nicotine for the fetus, the infant and the adolescent?

K. H. Ginzel, Gert S. Maritz, David F. Marks, Manfred Neuberger, Jim R. Pauly, John R. Polito, Rolf Schulte-Hermann, Theodore A. Slotkin

Research output: Contribution to journalReview articlepeer-review

74 Scopus citations


The recent expansion of Nicotine Replacement Therapy to pregnant women and children ignores the fact that nicotine impairs, disrupts, duplicates and/or interacts with essential physiological functions and is involved in tobacco-related carcinogenesis. The main concerns in the present context are its fetotoxicity and neuroteratogenicity that can cause cognitive, affective and behavioral disorders in children born to mothers exposed to nicotine during pregnancy, and the detrimental effects of nicotine on the growing organism. Hence, the use of nicotine, whose efficacy in treating nicotine addiction is controversial even in adults, must be strictly avoided in pregnancy, breastfeeding, childhood and adolescence.

Original languageEnglish
Pages (from-to)215-224
Number of pages10
JournalJournal of Health Psychology
Issue number2
StatePublished - Mar 2007


  • Adolescence
  • Carcinogenesis
  • Fetotoxicity
  • Nicotine Replacement Therapy
  • Pregnancy
  • Teratogenicity

ASJC Scopus subject areas

  • Applied Psychology


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