Cytokinin signaling promotes differential stability of type-B ARRs

Timothy E. Shull, Jasmina Kurepa, Jan A. Smalle

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Cytokinins control key aspects of plant growth, including shoot and root meristem development and the timing of senescence of leaves and stems. Cytokinin perception triggers a 2-component signaling mechanism that ultimately leads to phosphorylation-dependent activation of a class of transcriptional regulators called type-B ARRs (RRBs). We have recently shown that the stability of the RRB family member ARR1 is increased in response to elevated cytokinin concentrations. In contrast, cytokinin decreases the stability of the closely related RRB member ARR2. The molecular mechanism governing the differential stability regulation of these 2 closely related RRBs remains unknown.

Original languageEnglish
Article numbere1169354
JournalPlant Signaling and Behavior
Issue number4
StatePublished - 2016

Bibliographical note

Publisher Copyright:
© 2016 Taylor & Francis Group, LLC.


  • ARR1
  • ARR2
  • Cytokinin signaling
  • Proteasome
  • Protein stability
  • Type-A ARRs
  • Type-B ARRs

ASJC Scopus subject areas

  • Plant Science


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