Cholera toxin receptors are associated with the cytoskeletal residue of Triton X-100 extracts of rat erythrocytes. The solubilized cytoskeletal toxin-receptor complex appears to be a large macromolecular entity whose formation is facilitated by increased receptor occupancy. These findings suggest a role for GM1-gangliosides in transmembrane signalling and in the mechanism of action of cholera toxin.
|Number of pages||7|
|Journal||Biochemical and Biophysical Research Communications|
|State||Published - Oct 30 1981|
ASJC Scopus subject areas
- Molecular Biology
- Cell Biology