Abstract
Cholera toxin receptors are associated with the cytoskeletal residue of Triton X-100 extracts of rat erythrocytes. The solubilized cytoskeletal toxin-receptor complex appears to be a large macromolecular entity whose formation is facilitated by increased receptor occupancy. These findings suggest a role for GM1-gangliosides in transmembrane signalling and in the mechanism of action of cholera toxin.
Original language | English |
---|---|
Pages (from-to) | 1216-1222 |
Number of pages | 7 |
Journal | Biochemical and Biophysical Research Communications |
Volume | 102 |
Issue number | 4 |
DOIs | |
State | Published - Oct 30 1981 |
ASJC Scopus subject areas
- Biophysics
- Biochemistry
- Molecular Biology
- Cell Biology