d-amphetamine-induced enhancement of inhibitory mechanisms involved in visual search

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25 Scopus citations


The authors examined the effects of d-amphetamine on the ability to perform a cued target-detection task that measured inhibition of return (IOR). IOR is a reflexive inhibitory mechanism that delays attention from returning to a previously attended location and has been shown to increase the efficiency of a visual search. Adults (N = 14) with a history of cocaine use performed the task under 4 doses of d-amphetamine (0, 10, 20, and 30 mg). The results showed active d-amphetamine doses increased the duration of IOR. By increasing the delay in returning attention to a previously attended location, d-amphetamine might reduce time spent searching previously attended locations, increasing the efficiency of visual searches.

Original languageEnglish
Pages (from-to)200-208
Number of pages9
JournalExperimental and Clinical Psychopharmacology
Issue number3
StatePublished - Aug 2005


  • Amphetamine
  • Attention
  • Human
  • Inhibition
  • Stimulant

ASJC Scopus subject areas

  • Pharmacology
  • Psychiatry and Mental health
  • Pharmacology (medical)


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