Data correlations between gender, cytomegalovirus infection and T cells, NK cells, and soluble immune mediators in elderly humans

Ahmad Al-Attar; Steven R. Presnell; Charlotte A. Peterson; D. Travis Thomas; Charles T. Lutz

doi:10.1016/j.dib.2016.06.006

Data correlations between gender, cytomegalovirus infection and T cells, NK cells, and soluble immune mediators in elderly humans

Ahmad Al-Attar, Steven R. Presnell, Charlotte A. Peterson, D. Travis Thomas, Charles T. Lutz

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

We describe a cohort of 50 elderly subjects, age at least 70 years. We present gender-specific findings in T lymphocyte markers and soluble immune mediators. We show the correlation between cytomegalovirus infection status with CD56^dim NK cell responses to a variety of stimuli and with CD56^bright/CD56^dim NK cell ratio. We also present the correlation of retinol binding protein (RBP)-4 plasma levels with NK cell responses and we explore the relationship between gender and adiponectin, 25(OH)D (vitamin D), and RBP4 in affecting CD56^dim NK cell responses. These data are discussed in Al-Attar et al. (2016) [1].

Original language	English
Pages (from-to)	536-544
Number of pages	9
Journal	Data in Brief
Volume	8
DOIs	https://doi.org/10.1016/j.dib.2016.06.006
State	Published - Sep 1 2016

Bibliographical note

Funding Information:
We thank Jody Clasey, Doug Long, Kim Holt, Andrew J. Morris, Maja Redzic, Yuri M. Klyachkin, and CRO nurses for help with study subjects and data analysis. We thank Suzanne Segerstrom and Philip Westgate for statistical advice. This work was supported by NIH grant, AG040542 , and by University of Kentucky Center for Clinical and Translational Science Analytics Lab and CTSA funding UL1TR000117 .

Publisher Copyright:
© 2016 Published by Elsevier Inc.

Keywords

Adiponectin
Ageing
C-reactive protein
Cytomegalovirus
IL-15
NK cell
Retinol binding protein-4
Sex factors
Sphingosine-1-phosphate
T cell
Vitamin D

ASJC Scopus subject areas

General

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10.1016/j.dib.2016.06.006

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title = "Data correlations between gender, cytomegalovirus infection and T cells, NK cells, and soluble immune mediators in elderly humans",

abstract = "We describe a cohort of 50 elderly subjects, age at least 70 years. We present gender-specific findings in T lymphocyte markers and soluble immune mediators. We show the correlation between cytomegalovirus infection status with CD56dim NK cell responses to a variety of stimuli and with CD56bright/CD56dim NK cell ratio. We also present the correlation of retinol binding protein (RBP)-4 plasma levels with NK cell responses and we explore the relationship between gender and adiponectin, 25(OH)D (vitamin D), and RBP4 in affecting CD56dim NK cell responses. These data are discussed in Al-Attar et al. (2016) [1].",

keywords = "Adiponectin, Ageing, C-reactive protein, Cytomegalovirus, IL-15, NK cell, Retinol binding protein-4, Sex factors, Sphingosine-1-phosphate, T cell, Vitamin D",

author = "Ahmad Al-Attar and Presnell, {Steven R.} and Peterson, {Charlotte A.} and Thomas, {D. Travis} and Lutz, {Charles T.}",

note = "Funding Information: We thank Jody Clasey, Doug Long, Kim Holt, Andrew J. Morris, Maja Redzic, Yuri M. Klyachkin, and CRO nurses for help with study subjects and data analysis. We thank Suzanne Segerstrom and Philip Westgate for statistical advice. This work was supported by NIH grant, AG040542 , and by University of Kentucky Center for Clinical and Translational Science Analytics Lab and CTSA funding UL1TR000117 . Publisher Copyright: {\textcopyright} 2016 Published by Elsevier Inc.",

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AU - Al-Attar, Ahmad

AU - Presnell, Steven R.

AU - Peterson, Charlotte A.

AU - Thomas, D. Travis

AU - Lutz, Charles T.

N1 - Funding Information: We thank Jody Clasey, Doug Long, Kim Holt, Andrew J. Morris, Maja Redzic, Yuri M. Klyachkin, and CRO nurses for help with study subjects and data analysis. We thank Suzanne Segerstrom and Philip Westgate for statistical advice. This work was supported by NIH grant, AG040542 , and by University of Kentucky Center for Clinical and Translational Science Analytics Lab and CTSA funding UL1TR000117 . Publisher Copyright: © 2016 Published by Elsevier Inc.

PY - 2016/9/1

Y1 - 2016/9/1

N2 - We describe a cohort of 50 elderly subjects, age at least 70 years. We present gender-specific findings in T lymphocyte markers and soluble immune mediators. We show the correlation between cytomegalovirus infection status with CD56dim NK cell responses to a variety of stimuli and with CD56bright/CD56dim NK cell ratio. We also present the correlation of retinol binding protein (RBP)-4 plasma levels with NK cell responses and we explore the relationship between gender and adiponectin, 25(OH)D (vitamin D), and RBP4 in affecting CD56dim NK cell responses. These data are discussed in Al-Attar et al. (2016) [1].

AB - We describe a cohort of 50 elderly subjects, age at least 70 years. We present gender-specific findings in T lymphocyte markers and soluble immune mediators. We show the correlation between cytomegalovirus infection status with CD56dim NK cell responses to a variety of stimuli and with CD56bright/CD56dim NK cell ratio. We also present the correlation of retinol binding protein (RBP)-4 plasma levels with NK cell responses and we explore the relationship between gender and adiponectin, 25(OH)D (vitamin D), and RBP4 in affecting CD56dim NK cell responses. These data are discussed in Al-Attar et al. (2016) [1].

KW - Adiponectin

KW - Ageing

KW - C-reactive protein

KW - Cytomegalovirus

KW - IL-15

KW - NK cell

KW - Retinol binding protein-4

KW - Sex factors

KW - Sphingosine-1-phosphate

KW - T cell

KW - Vitamin D

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ER -

Data correlations between gender, cytomegalovirus infection and T cells, NK cells, and soluble immune mediators in elderly humans

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

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