Delayed death from pulmonary tuberculosis: Unsuspected subtherapeutic drug levels

Richard S. Morehead

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


A patient with fulminant pulmonary tuberculosis died after 41 days of intensive care despite pansensitive organisms and no known underlying immunosuppression. Two factors leading to death in this patient were a delay in seeking medical attention and a subtherapeutic serum level of rifampin, though no obvious evidence of malabsorption existed. Malabsorption of antitubercular drugs is under-recognized and of extreme importance in the treatment of critically ill patients with active pulmonary tuberculosis. Factors associated with mortality from tuberculosis and selected aspects of critical care management are discussed.

Original languageEnglish
Pages (from-to)507-510
Number of pages4
JournalSouthern Medical Journal
Issue number5
StatePublished - May 2000

ASJC Scopus subject areas

  • General Medicine


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