Delayed lead perforation: A disturbing trend

Mohammed N. Khan, George Joseph, Yaariv Khaykin, Khaled M. Ziada, Bruce L. Wilkoff

Research output: Contribution to journalArticlepeer-review

174 Scopus citations


Background: Delayed lead perforation (occurring more than 1 month after implantation) is a rare complication. Its pathophysiology and optimal management are currently unclear. Methods: Three cases of delayed lead perforation (6-10 month) were identified in patients with low-profile active fixation leads. Results: All cases presented in a subacute fashion with pleuritic chest pain with confirmatory chest x-ray and device interrogation. Given the potential complications of a perforated lead, all cases had the lead extracted under TEE observation with cardiac surgery backup in the operating room. All patients tolerated extraction without complication. Conclusion: Based on these cases, we recommend a management scheme for patients who present with delayed lead perforation.

Original languageEnglish
Pages (from-to)251-253
Number of pages3
JournalPACE - Pacing and Clinical Electrophysiology
Issue number3
StatePublished - Mar 2005


  • Lead perforation
  • Pacemaker extraction
  • Pericardium

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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