Demonstrating the potential of using transcutaneous oxygen and carbon dioxide tensions to assess the risk of pressure injuries

Mei Xue, Dandan Wang, Zhaozhi Zhang, Zhixin Cao, Zujin Luo, Yingying Zheng, Jingjing Lu, Qi Zhao, Xiaohua Douglas Zhang

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Pressure injuries have a high incidence in elderly and critically ill patients, and can endanger lives in severe cases. The key to reducing the incidence of pressure injuries is to find an objective, noninvasive, automatic and consistent scientific method for assessing pressure injuries. To serve this need, we conducted a clinical study to investigate the potential of using transcutaneous oxygen tension (TcPO2) and transcutaneous carbon dioxide tension (TcPCO2) for assessing pressure injuries. From the results of the study we found that first, the values of TcPO2 and TcPCO2 are sensitive to the change of pressure imposed on the measured region and to the risk status of a pressure injury when a pressure is imposed. Second, the magnitude of change in TcPO2 and TcPCO2 is higher in patients with a high risk of a pressure injury compared with those who have a low risk. Third, TcPO2 and TcPCO2 are both significantly correlated with the Braden score, the widely used score for assessing the risk of a pressure injury. Therefore, TcPO2 and TcPCO2 have a potential to be an effective and convenient scientific tool for assessing the risk of pressure injuries.

Original languageEnglish
Pages (from-to)1466-1471
Number of pages6
JournalInternational Journal of Biological Sciences
Issue number11
StatePublished - Aug 6 2018

Bibliographical note

Publisher Copyright:
© Ivyspring International Publisher.


  • Braden score
  • Pressure injury
  • Transcutaneous carbon dioxide tension
  • Transcutaneous oxygen tension

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Developmental Biology
  • Cell Biology


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