Depressive symptoms and dietary adherence in patients with end-stage renal disease

Amani A. Khalil, Susan K. Frazier, Terry A. Lennie, B. Peter Sawaya

Research output: Contribution to journalArticlepeer-review

62 Scopus citations


Depressive symptoms may be associated with fluid and dietary non adherence which could lead to poorer outcomes. The purpose of this study was to examine the relationship between depressive symptoms and fluid and dietary adherence in 100 patients with end-stage renal disease (ESRD) receiving haemodialysis. A descriptive, cross-sectional design with a convenience sample of 100 patients with ESRD receiving maintenance haemodialysis completed instruments that measured self-reported depressive symptoms and perceived fluid and dietary adherence. Demographic and clinical data and objective indicators of fluid and diet adherence were extracted from medical records. As many as two-third of these subjects exhibited depressive symptoms and half were non adherent to fluid and diet prescriptions. After controlling for known covariates, patients determined to have moderate to severe depressive symptoms were more likely to report non adherence to fluid and diet restrictions. Depressive symptoms in patients with ESRD are common and may contribute to dietary and fluid non adherence. Early identification and appropriate interventions may potentially lead to improvement in adherence of these patients.

Original languageEnglish
Pages (from-to)30-39
Number of pages10
JournalJournal of Renal Care
Issue number1
StatePublished - Mar 2011


  • Depressive symptoms
  • ESRD
  • Fluid and dietary non adherence
  • Haemodialysis

ASJC Scopus subject areas

  • Nephrology
  • Advanced and Specialized Nursing


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