Depressive symptoms and poor social support have a synergistic effect on event-free survival in patients with heart failure

Research output: Contribution to journalArticlepeer-review

34 Scopus citations

Abstract

Background: Depressive symptoms and poor social support are predictors of increased morbidity and mortality in patients with heart failure (HF). However, the combined contribution of depressive symptoms and social support event-free survival of patients with HF has not been examined. Objective: To compare event-free survival in 4 groups of patients with HF stratified by depressive symptoms and perceived social support (PSS). Method: A total of 220 patients completed the Beck Depression Inventory-II and the Multidimensional Perceived Social Support Scale and were followed for up to 4 years to collect data on death and hospitalizations. Results: Depressive symptoms (hazard ratio = 1.73, P = .008) and PSS (hazard ratio = 1.51, P = .048) were independent predictors of event-free survival. Depressed patients with low PSS had 2.1 times higher risk of events than non-depressed patients with high PSS (P = .003). Conclusion: Depressive symptoms and poor social support had a negative additive effect on event-free survival in patients with HF.

Original languageEnglish
Pages (from-to)492-501
Number of pages10
JournalHeart and Lung: Journal of Acute and Critical Care
Volume40
Issue number6
DOIs
StatePublished - Nov 2011

Keywords

  • Chronic Heart Failure
  • Depression
  • Outcomes
  • Social Support

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine
  • Cardiology and Cardiovascular Medicine

Fingerprint

Dive into the research topics of 'Depressive symptoms and poor social support have a synergistic effect on event-free survival in patients with heart failure'. Together they form a unique fingerprint.

Cite this