Depressive Symptoms Moderate the Association between Appetite and Health Status in Patients with Heart Failure

Christina Andreae, Anna Strömberg, Misook L. Chung, Carina Hjelm, Kristofer Årestedt

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Background: Decreased appetite and depressive symptoms are clinical problems in patients with heart failure. Both may result in impaired health status. Objective: The aims of this study were to investigate the association between appetite and health status in patients with heart failure and to explore whether depressive symptoms moderate this association. Methods: In this cross-sectional study, patients with heart failure (n = 186; mean age, 71 years), New York Heart Association class II to IV, participated. Data on appetite (Council of Nutrition Appetite Questionnaire), depressive symptoms (Patient Health Questionnaire-9), and health status (EQ-5D 3-level scale [EQ-5D-3L] descriptive system, EQ-5D-3L index, and EQ Visual Analog Scale) were collected by self-rating questionnaires. Pearson correlation was used to investigate the association between appetite and health status. Multiple regression was performed to examine whether depressive symptoms moderate the association between appetite and health status. Results: There was a significant association between appetite and health status for EQ-5D-3L descriptive system, mobility (P <.001), pain/discomfort (P <.001), and anxiety/depression (P <.001). This association was also shown in EQ-5D-3L index (P <.001) and EQ Visual Analog Scale (P <.001). Simple slope analysis showed that the association between appetite and health status was only significant for patients without depressive symptoms (B = 0.32, t = 4.66, P <.001). Conclusions: Higher level of appetite was associated with better health status. In moderation analysis, the association was presented for patients without depressive symptoms. Decreased appetite is an important sign of poor health status. To improve health status, health professionals should have greater attention on appetite, as well on signs of depressive symptoms.

Original languageEnglish
Pages (from-to)E15-E20
JournalJournal of Cardiovascular Nursing
Volume33
Issue number2
DOIs
StatePublished - Mar 1 2018

Bibliographical note

Publisher Copyright:
© 2018 Wolters Kluwer Health, Inc.

Keywords

  • Appetite
  • association
  • depression
  • health status
  • heart failure
  • nutritional status

ASJC Scopus subject areas

  • Medicine (all)

Fingerprint

Dive into the research topics of 'Depressive Symptoms Moderate the Association between Appetite and Health Status in Patients with Heart Failure'. Together they form a unique fingerprint.

Cite this