Design of the patient navigator to Reduce Readmissions (PArTNER) study: A pragmatic clinical effectiveness trial

Valentin Prieto-Centurion; Sanjib Basu; Nina Bracken; Elizabeth Calhoun; Carolyn Dickens; Robert J. DiDomenico; Richard Gallardo; Victor Gordeuk; Melissa Gutierrez-Kapheim; Lewis L. Hsu; Sai Illendula; Min Joo; Uzma Kazmi; Amelia Mutso; A. Simon Pickard; B. Pittendrigh; Jamie L. Sullivan; Mark Williams; Jerry A. Krishnan

doi:10.1016/j.conctc.2019.100420

Design of the patient navigator to Reduce Readmissions (PArTNER) study: A pragmatic clinical effectiveness trial

Valentin Prieto-Centurion, Sanjib Basu, Nina Bracken, Elizabeth Calhoun, Carolyn Dickens, Robert J. DiDomenico, Richard Gallardo, Victor Gordeuk, Melissa Gutierrez-Kapheim, Lewis L. Hsu, Sai Illendula, Min Joo, Uzma Kazmi, Amelia Mutso, A. Simon Pickard, B. Pittendrigh, Jamie L. Sullivan, Mark Williams, Jerry A. Krishnan

Internal Medicine

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Previous work indicates the potential for community health workers and peer coaches serving as patient navigators to improve processes of care and health outcomes during care transitions, but have not been sufficiently tested to determine if such programs improve measures of patient experience in minority serving institutions. The objectives of the Patient Navigator to Reduce Readmissions (PArTNER) study was to: 1) conduct a pragmatic clinical effectiveness trial comparing a multi-faceted, stakeholder-supported Navigator intervention (in-person CHW visits in the hospital and after hospital discharge, plus telephone-based peer coaching) versus usual care on the experience of hospital-to-home care transitions in patients hospitalized with heart failure, pneumonia, chronic obstructive pulmonary disease, myocardial infarction, or sickle cell disease; 2) examine the effectiveness of the Navigator intervention in patient subgroups; and 3) understand the barriers and facilitators of successfully implementing the Navigator intervention across patient populations. The co-primary outcomes are the 30-day changes in: 1) Patient Reported Outcomes Measurement Information System (PROMIS) emotional distress-anxiety, and 2) PROMIS informational support. Secondary outcomes at 30 and 60 days include other PROMIS health measures and hospital readmissions. Innovative features of the PArTNER study include early and continuous engagement of patients, their caregivers, clinicians, health system administrators, and other stakeholders to inform the design and implementation of the Navigator intervention. In this report, we describe the design of the PArTNER study.

Original language	English
Article number	100420
Journal	Contemporary Clinical Trials Communications
Volume	15
DOIs	https://doi.org/10.1016/j.conctc.2019.100420
State	Published - Sep 2019

Bibliographical note

Funding Information:
The PArTNER Study was funded through a Patient Centered Outcomes Research Institute (PCORI) award (contract # IH 12-11-4365 ; Clinicaltrails.gov registration # NCT02114515 ). The statements in this report are solely the responsibility of the authors and do not necessarily represent the views of PCORI, the PCORI Board of Governors, or the PCORI Methodology Committee.

Funding Information:
The PArTNER Study was funded through a Patient Centered Outcomes Research Institute (PCORI) award (contract # IH 12-11-4365; Clinicaltrails.gov registration #NCT02114515). The statements in this report are solely the responsibility of the authors and do not necessarily represent the views of PCORI, the PCORI Board of Governors, or the PCORI Methodology Committee. We gratefully acknowledge members of the external advisory committee (EAC) that meets once per year to provide input into study planning, implementation, synthesis, and dissemination activities. Members of the EAC include patients (Beatrice Bowie, Zandra Burton, Janice Cotton, Linda Reilly), caregivers (Jeanne Apelseth, Jacquelyn Canada), representatives of patient advocacy organization (Joel Africk [Respiratory Health Association], Marcia Baker [Mended Hearts], Bill Clark [COPD Foundation], TaLana Hughes [Sickle Cell Disease Association of Illinois], Bonnye Johnson [Sickle Cell Patient Council], Knitasha Washington [Consumers Advancing Patient Safety]), clinicians (Joan Zlotnik, social work, Eileen Collins, nurse, Robert Sandhaus, physician), and representatives of professional organizations (Meighan Girgus [American Heart Association], Erin Holve [AcademyHealth]). We also gratefully acknowledge members of the independent Data and Safety Monitoring Board (Andrew Auerbach, MD, MPH, Chair [University of California, San Francisco], Abigail Cook, PharmD, BCPS, [Loyola University], Margaret Fang, MD, [University of California, San Francisco], Lynn Reinke, PhD, ARNP, [University of Washington], and Eduard Vasilevskis, MD, [Vanderbilt University]). We also thank Eleanor Musick, BA, who assisted in developing a draft of this manuscript. We especially thank the patients, caregivers, and clinicians who helped us design the PArTNER study.

Publisher Copyright:
© 2019 The Authors

Keywords

Community health worker
Hospital readmissions
Hospital-to-home transition
Peer coaching
Pragmatic clinical trial

ASJC Scopus subject areas

Pharmacology

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10.1016/j.conctc.2019.100420

Cite this

Prieto-Centurion, V., Basu, S., Bracken, N., Calhoun, E., Dickens, C., DiDomenico, R. J., Gallardo, R., Gordeuk, V., Gutierrez-Kapheim, M., Hsu, L. L., Illendula, S., Joo, M., Kazmi, U., Mutso, A., Pickard, A. S., Pittendrigh, B., Sullivan, J. L., Williams, M., & Krishnan, J. A. (2019). Design of the patient navigator to Reduce Readmissions (PArTNER) study: A pragmatic clinical effectiveness trial. Contemporary Clinical Trials Communications, 15, Article 100420. https://doi.org/10.1016/j.conctc.2019.100420

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title = "Design of the patient navigator to Reduce Readmissions (PArTNER) study: A pragmatic clinical effectiveness trial",

abstract = "Previous work indicates the potential for community health workers and peer coaches serving as patient navigators to improve processes of care and health outcomes during care transitions, but have not been sufficiently tested to determine if such programs improve measures of patient experience in minority serving institutions. The objectives of the Patient Navigator to Reduce Readmissions (PArTNER) study was to: 1) conduct a pragmatic clinical effectiveness trial comparing a multi-faceted, stakeholder-supported Navigator intervention (in-person CHW visits in the hospital and after hospital discharge, plus telephone-based peer coaching) versus usual care on the experience of hospital-to-home care transitions in patients hospitalized with heart failure, pneumonia, chronic obstructive pulmonary disease, myocardial infarction, or sickle cell disease; 2) examine the effectiveness of the Navigator intervention in patient subgroups; and 3) understand the barriers and facilitators of successfully implementing the Navigator intervention across patient populations. The co-primary outcomes are the 30-day changes in: 1) Patient Reported Outcomes Measurement Information System (PROMIS) emotional distress-anxiety, and 2) PROMIS informational support. Secondary outcomes at 30 and 60 days include other PROMIS health measures and hospital readmissions. Innovative features of the PArTNER study include early and continuous engagement of patients, their caregivers, clinicians, health system administrators, and other stakeholders to inform the design and implementation of the Navigator intervention. In this report, we describe the design of the PArTNER study.",

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author = "Valentin Prieto-Centurion and Sanjib Basu and Nina Bracken and Elizabeth Calhoun and Carolyn Dickens and DiDomenico, {Robert J.} and Richard Gallardo and Victor Gordeuk and Melissa Gutierrez-Kapheim and Hsu, {Lewis L.} and Sai Illendula and Min Joo and Uzma Kazmi and Amelia Mutso and Pickard, {A. Simon} and B. Pittendrigh and Sullivan, {Jamie L.} and Mark Williams and Krishnan, {Jerry A.}",

note = "Funding Information: The PArTNER Study was funded through a Patient Centered Outcomes Research Institute (PCORI) award (contract # IH 12-11-4365 ; Clinicaltrails.gov registration # NCT02114515 ). The statements in this report are solely the responsibility of the authors and do not necessarily represent the views of PCORI, the PCORI Board of Governors, or the PCORI Methodology Committee. Funding Information: The PArTNER Study was funded through a Patient Centered Outcomes Research Institute (PCORI) award (contract # IH 12-11-4365; Clinicaltrails.gov registration #NCT02114515). The statements in this report are solely the responsibility of the authors and do not necessarily represent the views of PCORI, the PCORI Board of Governors, or the PCORI Methodology Committee. We gratefully acknowledge members of the external advisory committee (EAC) that meets once per year to provide input into study planning, implementation, synthesis, and dissemination activities. Members of the EAC include patients (Beatrice Bowie, Zandra Burton, Janice Cotton, Linda Reilly), caregivers (Jeanne Apelseth, Jacquelyn Canada), representatives of patient advocacy organization (Joel Africk [Respiratory Health Association], Marcia Baker [Mended Hearts], Bill Clark [COPD Foundation], TaLana Hughes [Sickle Cell Disease Association of Illinois], Bonnye Johnson [Sickle Cell Patient Council], Knitasha Washington [Consumers Advancing Patient Safety]), clinicians (Joan Zlotnik, social work, Eileen Collins, nurse, Robert Sandhaus, physician), and representatives of professional organizations (Meighan Girgus [American Heart Association], Erin Holve [AcademyHealth]). We also gratefully acknowledge members of the independent Data and Safety Monitoring Board (Andrew Auerbach, MD, MPH, Chair [University of California, San Francisco], Abigail Cook, PharmD, BCPS, [Loyola University], Margaret Fang, MD, [University of California, San Francisco], Lynn Reinke, PhD, ARNP, [University of Washington], and Eduard Vasilevskis, MD, [Vanderbilt University]). We also thank Eleanor Musick, BA, who assisted in developing a draft of this manuscript. We especially thank the patients, caregivers, and clinicians who helped us design the PArTNER study. Publisher Copyright: {\textcopyright} 2019 The Authors",

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doi = "10.1016/j.conctc.2019.100420",

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Prieto-Centurion, V, Basu, S, Bracken, N, Calhoun, E, Dickens, C, DiDomenico, RJ, Gallardo, R, Gordeuk, V, Gutierrez-Kapheim, M, Hsu, LL, Illendula, S, Joo, M, Kazmi, U, Mutso, A, Pickard, AS, Pittendrigh, B, Sullivan, JL, Williams, M & Krishnan, JA 2019, 'Design of the patient navigator to Reduce Readmissions (PArTNER) study: A pragmatic clinical effectiveness trial', Contemporary Clinical Trials Communications, vol. 15, 100420. https://doi.org/10.1016/j.conctc.2019.100420

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T1 - Design of the patient navigator to Reduce Readmissions (PArTNER) study

T2 - A pragmatic clinical effectiveness trial

AU - Prieto-Centurion, Valentin

AU - Basu, Sanjib

AU - Bracken, Nina

AU - Calhoun, Elizabeth

AU - Dickens, Carolyn

AU - DiDomenico, Robert J.

AU - Gallardo, Richard

AU - Gordeuk, Victor

AU - Gutierrez-Kapheim, Melissa

AU - Hsu, Lewis L.

AU - Illendula, Sai

AU - Joo, Min

AU - Kazmi, Uzma

AU - Mutso, Amelia

AU - Pickard, A. Simon

AU - Pittendrigh, B.

AU - Sullivan, Jamie L.

AU - Williams, Mark

AU - Krishnan, Jerry A.

N1 - Funding Information: The PArTNER Study was funded through a Patient Centered Outcomes Research Institute (PCORI) award (contract # IH 12-11-4365 ; Clinicaltrails.gov registration # NCT02114515 ). The statements in this report are solely the responsibility of the authors and do not necessarily represent the views of PCORI, the PCORI Board of Governors, or the PCORI Methodology Committee. Funding Information: The PArTNER Study was funded through a Patient Centered Outcomes Research Institute (PCORI) award (contract # IH 12-11-4365; Clinicaltrails.gov registration #NCT02114515). The statements in this report are solely the responsibility of the authors and do not necessarily represent the views of PCORI, the PCORI Board of Governors, or the PCORI Methodology Committee. We gratefully acknowledge members of the external advisory committee (EAC) that meets once per year to provide input into study planning, implementation, synthesis, and dissemination activities. Members of the EAC include patients (Beatrice Bowie, Zandra Burton, Janice Cotton, Linda Reilly), caregivers (Jeanne Apelseth, Jacquelyn Canada), representatives of patient advocacy organization (Joel Africk [Respiratory Health Association], Marcia Baker [Mended Hearts], Bill Clark [COPD Foundation], TaLana Hughes [Sickle Cell Disease Association of Illinois], Bonnye Johnson [Sickle Cell Patient Council], Knitasha Washington [Consumers Advancing Patient Safety]), clinicians (Joan Zlotnik, social work, Eileen Collins, nurse, Robert Sandhaus, physician), and representatives of professional organizations (Meighan Girgus [American Heart Association], Erin Holve [AcademyHealth]). We also gratefully acknowledge members of the independent Data and Safety Monitoring Board (Andrew Auerbach, MD, MPH, Chair [University of California, San Francisco], Abigail Cook, PharmD, BCPS, [Loyola University], Margaret Fang, MD, [University of California, San Francisco], Lynn Reinke, PhD, ARNP, [University of Washington], and Eduard Vasilevskis, MD, [Vanderbilt University]). We also thank Eleanor Musick, BA, who assisted in developing a draft of this manuscript. We especially thank the patients, caregivers, and clinicians who helped us design the PArTNER study. Publisher Copyright: © 2019 The Authors

PY - 2019/9

Y1 - 2019/9

N2 - Previous work indicates the potential for community health workers and peer coaches serving as patient navigators to improve processes of care and health outcomes during care transitions, but have not been sufficiently tested to determine if such programs improve measures of patient experience in minority serving institutions. The objectives of the Patient Navigator to Reduce Readmissions (PArTNER) study was to: 1) conduct a pragmatic clinical effectiveness trial comparing a multi-faceted, stakeholder-supported Navigator intervention (in-person CHW visits in the hospital and after hospital discharge, plus telephone-based peer coaching) versus usual care on the experience of hospital-to-home care transitions in patients hospitalized with heart failure, pneumonia, chronic obstructive pulmonary disease, myocardial infarction, or sickle cell disease; 2) examine the effectiveness of the Navigator intervention in patient subgroups; and 3) understand the barriers and facilitators of successfully implementing the Navigator intervention across patient populations. The co-primary outcomes are the 30-day changes in: 1) Patient Reported Outcomes Measurement Information System (PROMIS) emotional distress-anxiety, and 2) PROMIS informational support. Secondary outcomes at 30 and 60 days include other PROMIS health measures and hospital readmissions. Innovative features of the PArTNER study include early and continuous engagement of patients, their caregivers, clinicians, health system administrators, and other stakeholders to inform the design and implementation of the Navigator intervention. In this report, we describe the design of the PArTNER study.

AB - Previous work indicates the potential for community health workers and peer coaches serving as patient navigators to improve processes of care and health outcomes during care transitions, but have not been sufficiently tested to determine if such programs improve measures of patient experience in minority serving institutions. The objectives of the Patient Navigator to Reduce Readmissions (PArTNER) study was to: 1) conduct a pragmatic clinical effectiveness trial comparing a multi-faceted, stakeholder-supported Navigator intervention (in-person CHW visits in the hospital and after hospital discharge, plus telephone-based peer coaching) versus usual care on the experience of hospital-to-home care transitions in patients hospitalized with heart failure, pneumonia, chronic obstructive pulmonary disease, myocardial infarction, or sickle cell disease; 2) examine the effectiveness of the Navigator intervention in patient subgroups; and 3) understand the barriers and facilitators of successfully implementing the Navigator intervention across patient populations. The co-primary outcomes are the 30-day changes in: 1) Patient Reported Outcomes Measurement Information System (PROMIS) emotional distress-anxiety, and 2) PROMIS informational support. Secondary outcomes at 30 and 60 days include other PROMIS health measures and hospital readmissions. Innovative features of the PArTNER study include early and continuous engagement of patients, their caregivers, clinicians, health system administrators, and other stakeholders to inform the design and implementation of the Navigator intervention. In this report, we describe the design of the PArTNER study.

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Design of the patient navigator to Reduce Readmissions (PArTNER) study: A pragmatic clinical effectiveness trial

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Bibliographical note

Keywords

ASJC Scopus subject areas

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