TY - JOUR
T1 - Designing Liver Resections and Pushing the Envelope with Resections for Hepatic Colorectal Metastases
AU - Guye, Mary L.
AU - Schoellhammer, Hans F.
AU - Chiu, Louisa W.
AU - Kim, Joseph
AU - Lai, Lily L.
AU - Singh, Gagandeep
PY - 2013/12
Y1 - 2013/12
N2 - Current concepts in the management of hepatic metastases have changed dramatically over the past two decades. Multidisciplinary therapies including chemotherapy, surgery, and regional therapy have alone and in combination significantly improved the survival of patients with metastatic colorectal cancer. Conditions that were previously considered hopeless and treated merely for palliation can now be approached with curative intent. In this paper, we review the surgical treatment for colorectal cancer liver metastasis (CRLM) and describe a paradigm-shift in the management of complex heretofore-considered unresectable CRLM. Utilizing advanced multidisciplinary treatment strategies has improved the prognosis of patients with stage IV colorectal cancer to the point where we may question whether CRLM are now a chronic disease.
AB - Current concepts in the management of hepatic metastases have changed dramatically over the past two decades. Multidisciplinary therapies including chemotherapy, surgery, and regional therapy have alone and in combination significantly improved the survival of patients with metastatic colorectal cancer. Conditions that were previously considered hopeless and treated merely for palliation can now be approached with curative intent. In this paper, we review the surgical treatment for colorectal cancer liver metastasis (CRLM) and describe a paradigm-shift in the management of complex heretofore-considered unresectable CRLM. Utilizing advanced multidisciplinary treatment strategies has improved the prognosis of patients with stage IV colorectal cancer to the point where we may question whether CRLM are now a chronic disease.
KW - Colorectal cancer (CRC)
KW - hepatectomy
KW - liver resection
KW - metastasectomy
KW - metastatic colorectal cancer (mCRC)
KW - surgical management, survival
UR - http://www.scopus.com/inward/record.url?scp=84891896847&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84891896847&partnerID=8YFLogxK
U2 - 10.1007/s13193-013-0256-5
DO - 10.1007/s13193-013-0256-5
M3 - Review article
AN - SCOPUS:84891896847
SN - 0975-7651
VL - 4
SP - 349
EP - 355
JO - Indian Journal of Surgical Oncology
JF - Indian Journal of Surgical Oncology
IS - 4
ER -
