Destruction of a destructor: A new avenue for cancer therapeutics targeting the Wnt pathway

Chunming Liu; Xi He

doi:10.1093/jmcb/mjp040

Destruction of a destructor: A new avenue for cancer therapeutics targeting the Wnt pathway

Chunming Liu, Xi He

Molecular and Cellular Biochemistry

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

A new study in Nature has identified a small molecule inhibitor for the oncogenic Wnt/β-catenin pathway that is responsible for many human cancers. This inhibitor targets an unsuspected cellular enzyme, Tankyrase, which controls the destruction of a β-catenin destructor.

Original language	English
Pages (from-to)	70-73
Number of pages	4
Journal	Journal of Molecular Cell Biology
Volume	2
Issue number	2
DOIs	https://doi.org/10.1093/jmcb/mjp040
State	Published - 2010

ASJC Scopus subject areas

Molecular Biology
Genetics
Cell Biology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1093/jmcb/mjp040

Cite this

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title = "Destruction of a destructor: A new avenue for cancer therapeutics targeting the Wnt pathway",

abstract = "A new study in Nature has identified a small molecule inhibitor for the oncogenic Wnt/β-catenin pathway that is responsible for many human cancers. This inhibitor targets an unsuspected cellular enzyme, Tankyrase, which controls the destruction of a β-catenin destructor.",

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Destruction of a destructor: A new avenue for cancer therapeutics targeting the Wnt pathway

Abstract

ASJC Scopus subject areas

UN SDGs

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