Abstract
A series of novel temperature responsive hydrogels were synthesized by free radical polymerization with varying content of chrysin multiacrylate (ChryMA). The goal was to study the impact of this novel polyphenolic-based multiacrylate on the properties of N-isopropylacrylamide (NIPAAm) hydrogels. The temperature responsive behavior of the copolymerized gels was characterized by swelling studies, and their lower critical solution temperature (LCST) was characterized through differential scanning calorimetry (DSC). It was shown that the incorporation of ChryMA decreased the swelling ratios of the hydrogels and shifted their LCSTs to a lower temperature. Gels with different ChryMA content showed different levels of response to temperature change. Higher content gels had a broader phase transition and smaller temperature response, which could be attributed to the increased hydrophobicity being introduced by the ChryMA.
| Original language | English |
|---|---|
| Article number | 40 |
| Journal | Gels |
| Volume | 3 |
| Issue number | 4 |
| DOIs | |
| State | Published - Dec 2017 |
Bibliographical note
Publisher Copyright:© 2017 by the authors. Licensee MDPI, Basel, Switzerland.
Funding
Acknowledgments: This research has been generously supported by the National Institute of Environmental Health Sciences (NIEHS) (Project No: P42ES007380) and the National Science Foundation REU Program (Project No: EEC-1460486).
| Funders | Funder number |
|---|---|
| National Science Foundation (NSF) | EEC-1460486 |
| National Institute of Environmental Health Sciences (NIEHS) | P42ES007380 |
Keywords
- Hydrogel
- LCST
- N-isopropylacrylamide
ASJC Scopus subject areas
- Bioengineering
- Biomaterials
- Organic Chemistry
- Polymers and Plastics