Abstract
Previous studies show that the developing circadian system is entrained by a maternal signal during the prenatal and early postnatal period. The present study investigated the developmental onset of retina-mediated, light-dark entrainment. Juvenile rats were exposed to phase-shifts in the light-dark cycle at different ages and the pineal N-acetyltransferase rhythm was monitored on postnatal day 10. The results show that retina-mediated, light-dark entrainment begins by postnatal day 6 and overrides maternal entrainment by postnatal day 8.
Original language | English |
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Pages (from-to) | 326-330 |
Number of pages | 5 |
Journal | Brain Research |
Volume | 369 |
Issue number | 1-2 |
DOIs | |
State | Published - Mar 26 1986 |
Bibliographical note
Funding Information:This work was supported by Public Health Service Grant HD 14427 and March of Dimes Research Grant No. 1-945. S.M.R. is an Established Investigator of the American Heart Association.
Keywords
- circadian rhythm
- entrainment
- pineal gland
- suprachiasmatic nucleus
ASJC Scopus subject areas
- General Neuroscience
- Molecular Biology
- Clinical Neurology
- Developmental Biology