Abstract
Previous studies show that the developing circadian system is entrained by a maternal signal during the prenatal and early postnatal period. The present study investigated the developmental onset of retina-mediated, light-dark entrainment. Juvenile rats were exposed to phase-shifts in the light-dark cycle at different ages and the pineal N-acetyltransferase rhythm was monitored on postnatal day 10. The results show that retina-mediated, light-dark entrainment begins by postnatal day 6 and overrides maternal entrainment by postnatal day 8.
| Original language | English |
|---|---|
| Pages (from-to) | 326-330 |
| Number of pages | 5 |
| Journal | Brain Research |
| Volume | 369 |
| Issue number | 1-2 |
| DOIs | |
| State | Published - Mar 26 1986 |
Bibliographical note
Funding Information:This work was supported by Public Health Service Grant HD 14427 and March of Dimes Research Grant No. 1-945. S.M.R. is an Established Investigator of the American Heart Association.
Funding
This work was supported by Public Health Service Grant HD 14427 and March of Dimes Research Grant No. 1-945. S.M.R. is an Established Investigator of the American Heart Association.
| Funders | Funder number |
|---|---|
| March of Dimes Research Foundation | 1-945 |
| U.S. Public Health Service | |
| Eunice Kennedy Shriver National Institute of Child Health and Human Development | R37HD014427 |
Keywords
- circadian rhythm
- entrainment
- pineal gland
- suprachiasmatic nucleus
ASJC Scopus subject areas
- General Neuroscience
- Molecular Biology
- Clinical Neurology
- Developmental Biology