Developmental plasticity shapes social traits and selection in a facultatively eusocial bee

Karen M. Kapheim, Beryl M. Jones, Hailin Pan, Cai Li, Brock A. Harpur, Clement F. Kent, Amro Zayed, Panagiotis Ioannidis, Robert M. Waterhouse, Callum Kingwell, Eckart Stolle, Arián Avalos, Guojie Zhang, W. Owen McMillan, William T. Wcislo

Research output: Contribution to journalArticlepeer-review

30 Scopus citations

Abstract

Developmental plasticity generates phenotypic variation, but how it contributes to evolutionary change is unclear. Phenotypes of individuals in caste-based (eusocial) societies are particularly sensitive to developmental processes, and the evolutionary origins of eusociality may be rooted in developmental plasticity of ancestral forms. We used an integrative genomics approach to evaluate the relationships among developmental plasticity, molecular evolution, and social behavior in a bee species (Megalopta genalis) that expresses flexible sociality, and thus provides a window into the factors that may have been important at the evolutionary origins of eusociality. We find that differences in social behavior are derived from genes that also regulate sex differentiation and metamorphosis. Positive selection on social traits is influenced by the function of these genes in development. We further identify evidence that social polyphenisms may become encoded in the genome via genetic changes in regulatory regions, specifically in transcription factor binding sites. Taken together, our results provide evidence that developmental plasticity provides the substrate for evolutionary novelty and shapes the selective landscape for molecular evolution in a major evolutionary innovation: Eusociality.

Original languageEnglish
Pages (from-to)13615-13625
Number of pages11
JournalProceedings of the National Academy of Sciences of the United States of America
Volume117
Issue number24
DOIs
StatePublished - Jun 16 2020

Bibliographical note

Publisher Copyright:
© 2020 National Academy of Sciences. All rights reserved.

Keywords

  • Gene regulation
  • Genetic accommodation
  • Megalopta genalis
  • Social evolution
  • Transcription factor binding

ASJC Scopus subject areas

  • General

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