Diabetes, left ventricular systolic dysfunction, and chronic heart failure

Michael R. MacDonald; Mark C. Petrie; Nathaniel M. Hawkins; John R. Petrie; Miles Fisher; Robert McKelvie; David Aguilar; Henry Krum; John J.V. McMurray

doi:10.1093/eurheartj/ehn156

Diabetes, left ventricular systolic dysfunction, and chronic heart failure

Michael R. MacDonald, Mark C. Petrie, Nathaniel M. Hawkins, John R. Petrie, Miles Fisher, Robert McKelvie, David Aguilar, Henry Krum, John J.V. McMurray

Internal Medicine

Research output: Contribution to journal › Review article › peer-review

205 Scopus citations

Abstract

Chronic heart failure (HF) and diabetes mellitus (DM) commonly coexist. Each condition increases the likelihood of developing the other, and when they occur together in the same patient the risk of morbidity and mortality increases markedly. We discuss the epidemiological overlap and consider the complex patho-physiological pathways linking the two diseases. The treatment of each condition is made more problematic by the presence of the other. We review the evidence-based treatment strategies and discuss the common problems faced by physicians when treating patients with both conditions. This article forms a comprehensive overview of a fascinating intersection between two common diseases.

Original language	English
Pages (from-to)	1224-1240
Number of pages	17
Journal	European Heart Journal
Volume	29
Issue number	10
DOIs	https://doi.org/10.1093/eurheartj/ehn156
State	Published - May 2008

Keywords

Diabetes
Heart failure

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1093/eurheartj/ehn156

Cite this

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title = "Diabetes, left ventricular systolic dysfunction, and chronic heart failure",

abstract = "Chronic heart failure (HF) and diabetes mellitus (DM) commonly coexist. Each condition increases the likelihood of developing the other, and when they occur together in the same patient the risk of morbidity and mortality increases markedly. We discuss the epidemiological overlap and consider the complex patho-physiological pathways linking the two diseases. The treatment of each condition is made more problematic by the presence of the other. We review the evidence-based treatment strategies and discuss the common problems faced by physicians when treating patients with both conditions. This article forms a comprehensive overview of a fascinating intersection between two common diseases.",

keywords = "Diabetes, Heart failure",

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T1 - Diabetes, left ventricular systolic dysfunction, and chronic heart failure

AU - MacDonald, Michael R.

AU - Petrie, Mark C.

AU - Hawkins, Nathaniel M.

AU - Petrie, John R.

AU - Fisher, Miles

AU - McKelvie, Robert

AU - Aguilar, David

AU - Krum, Henry

AU - McMurray, John J.V.

PY - 2008/5

Y1 - 2008/5

N2 - Chronic heart failure (HF) and diabetes mellitus (DM) commonly coexist. Each condition increases the likelihood of developing the other, and when they occur together in the same patient the risk of morbidity and mortality increases markedly. We discuss the epidemiological overlap and consider the complex patho-physiological pathways linking the two diseases. The treatment of each condition is made more problematic by the presence of the other. We review the evidence-based treatment strategies and discuss the common problems faced by physicians when treating patients with both conditions. This article forms a comprehensive overview of a fascinating intersection between two common diseases.

AB - Chronic heart failure (HF) and diabetes mellitus (DM) commonly coexist. Each condition increases the likelihood of developing the other, and when they occur together in the same patient the risk of morbidity and mortality increases markedly. We discuss the epidemiological overlap and consider the complex patho-physiological pathways linking the two diseases. The treatment of each condition is made more problematic by the presence of the other. We review the evidence-based treatment strategies and discuss the common problems faced by physicians when treating patients with both conditions. This article forms a comprehensive overview of a fascinating intersection between two common diseases.

KW - Diabetes

KW - Heart failure

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U2 - 10.1093/eurheartj/ehn156

DO - 10.1093/eurheartj/ehn156

M3 - Review article

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AN - SCOPUS:44449146547

SN - 0195-668X

VL - 29

SP - 1224

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JO - European Heart Journal

JF - European Heart Journal

IS - 10

ER -

Diabetes, left ventricular systolic dysfunction, and chronic heart failure

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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