Diagnosis and treatment of interstitial cystitis/bladder pain syndrome: AUA guideline amendment

Philip M. Hanno, Deborah Erickson, Robert Moldwin, Martha M. Faraday

Research output: Contribution to journalArticlepeer-review

431 Scopus citations


Purpose The purpose of this amendment is to provide an updated clinical framework for the diagnosis and treatment of interstitial cystitis/bladder pain syndrome based upon data received since the publication of original guideline in 2011. Materials and Methods A systematic literature review using the MEDLINE® database (search dates 1/1/83-7/22/09) was conducted to identify peer-reviewed publications relevant to the diagnosis and treatment of IC/BPS. This initial review yielded an evidence base of 86 treatment articles after application of inclusion/exclusion criteria. The AUA update literature review process, in which an additional systematic review is conducted periodically to maintain guideline currency with newly published relevant literature, was conducted in July 2013. This review identified an additional 31 articles, which were added to the evidence base of this Guideline. Results Newly incorporated literature describing the treatment of IC/BPS was integrated into the Guideline with additional treatment information provided as Clinical Principles and Expert Opinions when insufficient evidence existed. The diagnostic portion of the Guideline remains unchanged from the original publication and is still based on Expert Opinions and Clinical Principles. Conclusions The management of IC/BPS continues to evolve as can be seen by an expanding literature on the topic. This document constitutes a clinical strategy and is not intended to be interpreted rigidly. The most effective approach for a particular patient is best determined by the individual clinician and patient. As the science relevant to IC/BPS evolves and improves, the strategies presented will require amendment to remain consistent with the highest standards of care.

Original languageEnglish
Pages (from-to)1545-1553
Number of pages9
JournalJournal of Urology
Issue number5
StatePublished - May 1 2015

Bibliographical note

Publisher Copyright:
© 2015 American Urological Association Education and Research, Inc.


  • cystitis
  • interstitial
  • lower urinary tract symptoms
  • pelvic pain
  • urinary bladder diseases
  • urodynamics

ASJC Scopus subject areas

  • Urology


Dive into the research topics of 'Diagnosis and treatment of interstitial cystitis/bladder pain syndrome: AUA guideline amendment'. Together they form a unique fingerprint.

Cite this