Diagnostic stability and evolution of bipolar disorder in clinical practice: A prospective cohort study

E. Baca-Garcia, M. M. Perez-Rodriguez, I. Basurte-Villamor, J. López-Castromán, A. L. Fernandez Del Moral, M. A. Jimenez-Arriero, J. L. Gronzalez De Rivera, J. Saiz-Ruiz, J. M. Leiva-Murillo, M. De Prado-Cumplido, R. Santiago-Mozos, A. Artés-Rodríguez, M. A. Oquendo, J. De Leon

Research output: Contribution to journalArticlepeer-review

51 Scopus citations

Abstract

Objective: To evaluate the long-term stability of International Classification of Diseases-10th revision bipolar affective disorder (BD) in multiple settings. Method: A total of 34 368 patients received psychiatric care in the catchment area of a Spanish hospital (1992-2004). The analyzed sample included patients aged ≥18 years who were assessed on ≥10 occasions and received a diagnosis of BD at least once (n = 1153; 71 543 assessments). Prospective and retrospective consistencies and the proportion of subjects who received a BD diagnosis in ≥75% of assessments were calculated. Factors related to diagnostic shift were analyzed with traditional statistical methods and Markov's models. Results: Thirty per cent of patients received a BD diagnosis in the first assessment and 38% in the last assessment. Prospective and retrospective consistencies were 49% and 38%. Twenty-three per cent of patients received a BD diagnosis during ≥75% of the assessments. Conclusion: There was a high prevalence of misdiagnosis and diagnostic shift from other psychiatric disorders to BD. Temporal consistency was lower than in other studies.

Original languageEnglish
Pages (from-to)473-480
Number of pages8
JournalActa Psychiatrica Scandinavica
Volume115
Issue number6
DOIs
StatePublished - Jun 2007

Keywords

  • Bipolar disorder
  • Classification
  • Diagnosis
  • International Classification of Diseases
  • Reproducibility of results

ASJC Scopus subject areas

  • Psychiatry and Mental health

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