Dielectric modulation of biological water

Florin Despa; Ariel Fernández; R. Stephen Berry

doi:10.1103/PhysRevLett.93.228104

Dielectric modulation of biological water

Florin Despa, Ariel Fernández, R. Stephen Berry

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100 Scopus citations

Abstract

A model which shows the librational dynamics undergone by water constrained by vicinal hydrophobes, which lowers the dielectric susceptibility and induces a 'redshift' of the relaxation frequency in the hydration shell was presented. The reduction of H-bond exchange possibilities of water molecules at a hydrophobic interface was analyzed. Water molecules were found to exchange H bonds with neighbours at a fast rate (V_b ≅1.7 × 10 ¹³ s^-1 at room temperature. The results also demonstrated the way in which proteins enhance their intramolecular interactions as they fold or associate.

Original language	English
Article number	228104
Journal	Physical Review Letters
Volume	93
Issue number	22
DOIs	https://doi.org/10.1103/PhysRevLett.93.228104
State	Published - Nov 29 2004

Bibliographical note

Funding Information:
We acknowledge the support of a grant from the National Science Foundation.

Funding

We acknowledge the support of a grant from the National Science Foundation.

Funders	Funder number
National Science Foundation (NSF)

ASJC Scopus subject areas

General Physics and Astronomy

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10.1103/PhysRevLett.93.228104

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Dielectric modulation of biological water

Abstract

Bibliographical note

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ASJC Scopus subject areas

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