TY - JOUR
T1 - Dietary modulation of the inflammatory cascade
AU - Dawson, Dolphus R.
AU - Branch-Mays, Grishondra
AU - Gonzalez, Octavio A.
AU - Ebersole, Jeffrey L.
PY - 2014/2
Y1 - 2014/2
N2 - Dietary supplementation has traditionally consisted of adding vitamins and/or minerals to correct or prevent a nutritional deficiency. When supplementing the diet with other inflammatory mediators, such as essential fatty acids, there is an adjunctive benefit to the standard therapies used in the control of chronic inflammatory diseases such as Crohn's disease or rheumatoid arthritis. This review focuses on the strategies utilized for therapeutic modulation of the inflammatory cascade through dietary supplementation with specific biomolecules. Examples of how these biomolecules affect local and systemic immune responses to chronic inflammation are examined. In particular, an overview of the literature identifying the potential to modify the host response to chronic periodontitis is provided.
AB - Dietary supplementation has traditionally consisted of adding vitamins and/or minerals to correct or prevent a nutritional deficiency. When supplementing the diet with other inflammatory mediators, such as essential fatty acids, there is an adjunctive benefit to the standard therapies used in the control of chronic inflammatory diseases such as Crohn's disease or rheumatoid arthritis. This review focuses on the strategies utilized for therapeutic modulation of the inflammatory cascade through dietary supplementation with specific biomolecules. Examples of how these biomolecules affect local and systemic immune responses to chronic inflammation are examined. In particular, an overview of the literature identifying the potential to modify the host response to chronic periodontitis is provided.
UR - http://www.scopus.com/inward/record.url?scp=84889665631&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84889665631&partnerID=8YFLogxK
U2 - 10.1111/j.1600-0757.2012.00458.x
DO - 10.1111/j.1600-0757.2012.00458.x
M3 - Article
C2 - 24320963
AN - SCOPUS:84889665631
SN - 0906-6713
VL - 64
SP - 161
EP - 197
JO - Periodontology 2000
JF - Periodontology 2000
IS - 1
ER -