Dietary selenium and liver cancer

Divinia N. Stemm; Howard P. Glauert

doi:10.1201/b10330

Dietary selenium and liver cancer

Divinia N. Stemm, Howard P. Glauert

Pharmacology and Nutritional Sciences

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Dietary selenium (Se) is an essential mineral for both humans and animals. It functions as a component of several proteins, termed selenoproteins. These include glutathione peroxidases (GPx, several different isoforms), thioredoxin reductases (three isoforms), iodothyronine deiodinases (three isoforms), selenophosphate synthetase, selenoprotein P, and selenoprotein W (Burk and Levander, 2006). Because glutathione peroxidase and thioredoxin reductase function as antioxidants and because an inverse relationship between selenium intake and cancer risk was identified in several studies, increasing selenium intake has been proposed as a way to prevent the development of some forms of cancer in humans.

Original language	English
Title of host publication	Bioactive Foods and Extracts
Subtitle of host publication	Cancer Treatment and Prevention
Pages	497-504
Number of pages	8
ISBN (Electronic)	9781439816219
DOIs	https://doi.org/10.1201/b10330
State	Published - Jan 1 2010

Bibliographical note

Publisher Copyright:
© 2010 by Taylor & Francis Group, LLC.

ASJC Scopus subject areas

General Medicine
General Engineering
General Agricultural and Biological Sciences

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1201/b10330

Cite this

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AB - Dietary selenium (Se) is an essential mineral for both humans and animals. It functions as a component of several proteins, termed selenoproteins. These include glutathione peroxidases (GPx, several different isoforms), thioredoxin reductases (three isoforms), iodothyronine deiodinases (three isoforms), selenophosphate synthetase, selenoprotein P, and selenoprotein W (Burk and Levander, 2006). Because glutathione peroxidase and thioredoxin reductase function as antioxidants and because an inverse relationship between selenium intake and cancer risk was identified in several studies, increasing selenium intake has been proposed as a way to prevent the development of some forms of cancer in humans.

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Dietary selenium and liver cancer

Abstract

Bibliographical note

ASJC Scopus subject areas

UN SDGs

Access to Document

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