Dietary selenium and liver cancer

Divinia N. Stemm, Howard P. Glauert

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Dietary selenium (Se) is an essential mineral for both humans and animals. It functions as a component of several proteins, termed selenoproteins. These include glutathione peroxidases (GPx, several different isoforms), thioredoxin reductases (three isoforms), iodothyronine deiodinases (three isoforms), selenophosphate synthetase, selenoprotein P, and selenoprotein W (Burk and Levander, 2006). Because glutathione peroxidase and thioredoxin reductase function as antioxidants and because an inverse relationship between selenium intake and cancer risk was identified in several studies, increasing selenium intake has been proposed as a way to prevent the development of some forms of cancer in humans.

Original languageEnglish
Title of host publicationBioactive Foods and Extracts
Subtitle of host publicationCancer Treatment and Prevention
Number of pages8
ISBN (Electronic)9781439816219
StatePublished - Jan 1 2010

Bibliographical note

Publisher Copyright:
© 2010 by Taylor & Francis Group, LLC.

ASJC Scopus subject areas

  • General Medicine
  • General Engineering
  • General Agricultural and Biological Sciences


Dive into the research topics of 'Dietary selenium and liver cancer'. Together they form a unique fingerprint.

Cite this