TY - JOUR
T1 - Differences in Vitamin D Nutritional Status Between Newly Diagnosed Cancer Patients from Rural or Urban Settings in Kentucky
AU - Christopher, K. L.
AU - Thaxton Wiggins, Amanda
AU - Van Meter, E. M.
AU - Means, Jr., R. T.
AU - Hayslip, J. W.
AU - Roach, J. P.
PY - 2013/7
Y1 - 2013/7
N2 - Although poor nutritional status and weight loss in cancer patients is known to affect outcomes, little is known about malnutrition differences based on geographic location. We investigated nutritional and inflammatory status of 220 newly diagnosed adults with solid tumors at the University of Kentucky's Markey Cancer Center during December 2008 through October 2011. Chi-square tests were used to determine any associations between suboptimal nutritional levels and rural–urban areas of residence. Out of the 13 lab values collected, the only significant difference between rural and urban participants was found for vitamin D resulting in more rural subjects (67.4%) having a suboptimal vitamin D status as compared to those residing in urban areas (53.3%, P = 0.04). Controlling for baseline demographics including age, race, sex, body mass index, nutritional status, and type of cancer, logistic regression analyses concluded those in rural areas had nearly a twofold increase in the odds of having a suboptimal vitamin D level compared to those in urban areas (odd's ratio = 1.97; 95% confidence interval = 1.04, 3.74). Further investigation into the rural–urban differences in vitamin D needs to be investigated in order to improve outcomes during cancer treatment.
AB - Although poor nutritional status and weight loss in cancer patients is known to affect outcomes, little is known about malnutrition differences based on geographic location. We investigated nutritional and inflammatory status of 220 newly diagnosed adults with solid tumors at the University of Kentucky's Markey Cancer Center during December 2008 through October 2011. Chi-square tests were used to determine any associations between suboptimal nutritional levels and rural–urban areas of residence. Out of the 13 lab values collected, the only significant difference between rural and urban participants was found for vitamin D resulting in more rural subjects (67.4%) having a suboptimal vitamin D status as compared to those residing in urban areas (53.3%, P = 0.04). Controlling for baseline demographics including age, race, sex, body mass index, nutritional status, and type of cancer, logistic regression analyses concluded those in rural areas had nearly a twofold increase in the odds of having a suboptimal vitamin D level compared to those in urban areas (odd's ratio = 1.97; 95% confidence interval = 1.04, 3.74). Further investigation into the rural–urban differences in vitamin D needs to be investigated in order to improve outcomes during cancer treatment.
U2 - 10.1080/01635581.2013.789117
DO - 10.1080/01635581.2013.789117
M3 - Article
SN - 0163-5581
VL - 65
SP - 653
EP - 658
JO - Nutrition and Cancer
JF - Nutrition and Cancer
IS - 5
ER -